Clinical trialNCT01206062CompletedInterventional

Systolic Blood Pressure Intervention Trial

SponsorNational Heart, Lung, and Blood Institute (NHLBI)Enrollment9,361Hypertension

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Elevated blood pressure (BP) is an important public health concern. It is highly prevalent, the prevalence may be increasing, and it is a risk factor for several adverse health outcomes, especially coronary heart disease, stroke, heart failure, chronic kidney disease, and decline in cognitive function. The Systolic Blood Pressure Intervention Trial (SPRINT) is a 2-arm, multicenter, randomized clinical trial designed to test whether a treatment program aimed at reducing systolic blood pressure (SBP) to a lower goal than currently recommended will reduce cardiovascular disease (CVD) risk.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alfred Cheung, MD
University of Utah
Principal Investigator
clinicaltrials.gov ↗
Bill Cushman, MD
Memphis VA Medical Center
Principal Investigator
clinicaltrials.gov ↗
David M. Reboussin, PhD
Wake Forest University Health Sciences
Principal Investigator
clinicaltrials.gov ↗
Jackson T Wright, MD
Case Western Reserve University
Principal Investigator
clinicaltrials.gov ↗
Mike Rocco, MD
Wake Forest University Health Sciences
Principal Investigator
clinicaltrials.gov ↗
Suzanne Oparil, MD
University of Alabama at Birmingham
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Wake Forest University School of Medicine
Winston-Salem, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Intensive control of SBPStandard control of SBP

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2010
Primary completion: 31 Jul 2016
Completion: 31 Mar 2019
Last update posted: 8 Jan 2021
Registered enrollment: 9,361
Registry id: NCT01206062

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.