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Clinical trialNCT01209754CompletedObservational

EMBRACE (Evaluation of Maternal and Baby Outcome Registry After Chemoprophylactic Exposure)

SponsorMicrobicide Trials NetworkEnrollment873Pregnancy Related
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The Prevention Agent Pregnancy Exposure Registry, also known as EMBRACE (Evaluation of Maternal and Baby Outcome Registry After Chemoprophylactic Exposure) is a prospective observational cohort investigation of exposures to study agents under investigation for HIV prevention. The study population will consist of female participants who are identified as becoming pregnant during their participation in a microbicide or PrEP trial, or who have had planned exposures in pregnancy safety studies as well as their babies resulting from these pregnancies. This study will only enroll babies who have not yet reached their 1 year birth date.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

17 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

South Africa
  • Wits Reproductive Health Institute (wrhi)

    Johannesburg, Gauteng, South Africa

  • Caprisa-the Aurum Institute

    Johannesburg, Guateng, South Africa

  • Caprisa Ethekwini

    Durban, KwaZulu-Natal, South Africa

  • Perinatal Hiv Research Unit (phru)

    Johannesburg, Soweto, South Africa

  • South African Mrc Hiv Ctu Med Research Council; Botha'S Hill Clinical Research Site

    Durban, South Africa

  • South African Mrc Hiv Ctu Med Research Council; Isipingo

    Durban, South Africa

  • South African Mrc Hiv Ctu Med Research Council; Overport

    Durban, South Africa

  • South African Mrc Hiv Ctu Med Research Council; R.K. Khan Hospital

    Durban, South Africa

  • South African Mrc Hiv Ctu Med Research Council; Tongaat

    Durban, South Africa

  • South African Mrc Hiv Ctu Med Research Council; Umkomaas

    Durban, South Africa

  • South African Mrc Hiv Ctu Med Research Council; Verulam

    Durban, South Africa

Uganda
  • Makerere University-Johns Hopkins University Collaboration

    Kampala, Uganda

United States
  • University of Alabama at Birmingham

    Birmingham, Alabama, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, United States

Zimbabwe
  • Uz-Ucsf Hiv Prevention Trials Unit

    Chitungwiza, Seke South, Zimbabwe

  • Uz-Ucsf Hiv Prevention Trials Unit

    Harare, Spilhaus, Zimbabwe

  • Uz-Ucsf Hiv Prevention Trials Unit

    Chitungwiza, Zengeza, Zimbabwe

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Oct 2009
Primary completion
6 May 2020
Completion
6 May 2020
Last update posted
21 Jun 2021
Registered enrollment
873
Registry id
NCT01209754
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.