Clinical trialNCT01225562CompletedPhase 3Interventional

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin

SponsorAstraZenecaEnrollment21,379AtherothrombosisCardiovascular DeathMyocardial InfarctionStroke

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is being carried out to see if a new drug called ticagrelor given twice daily in addition to the ASA therapy decreases the frequency of cardiovascular events (e.g., death from heart disease, heart attack, or stroke).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Eugene Braunwald, MD
The TIMI Study Group
Study Chair
clinicaltrials.gov ↗
Marc Sabatine, MD, MPh
The TIMI Study Group
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

826 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Argentina

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Bahía Blanca, Argentina
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Buenos Aires, Argentina
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Ciudad Autonoma de BA, Argentina
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Ciudad de Buenos Aires, Argentina
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Ciudadela, Argentina
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Coronel Suárez, Argentina
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Corrientes, Argentina
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Córdoba, Argentina
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Haedo, Argentina
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La Plata, Argentina
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Mar del Plata, Argentina
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Ramos Mejía, Argentina
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Rosario, Argentina
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Rosario Santa Fe, Argentina
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San Luis, Argentina
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San Miguel de Tucumán, Argentina
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San Nicolás, Argentina
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San Salvador de Jujuy, Argentina
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Santa Fe, Argentina
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Zárate, Argentina

Australia

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Adelaide, Australia
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Ashford, Australia
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Auchenflower, Australia
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Ballarat, Australia
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Bruce, Australia
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Chermside, Australia
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Clayton, Australia
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Concord, Australia
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East Saint Kilda, Australia
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Elizabeth Vale, Australia
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Epping, Australia
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Fremantle, Australia
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Geelong, Australia
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Gosford, Australia
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Greenslopes, Australia
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Herston, Australia
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Joondalup, Australia
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Kingswood, Australia
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Kogorah, Australia
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Launceston, Australia

786 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Ticagrelor →Ticagrelor Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2010
Primary completion: 31 Dec 2014
Completion: 31 Dec 2014
Last update posted: 25 Jan 2016
Registered enrollment: 21,379
Registry id: NCT01225562

Cross-registrations

EU-CTR / CTIS (EudraCT)2009-017242-30

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.