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Clinical trialNCT01245335CompletedPhase 3Interventional

Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI)

SponsorHarvest TechnologiesEnrollment97Critical Limb Ischemia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Critical Limb Ischemia prevents the legs and feet from receiving oxygen and nutrients needed for proper function. This severe lack of blood flow can lead to painful legs while walking or at rest and can result in foot sores, ulcers, gangrene, and even amputation. The purpose of this study is to determine if injections of concentrated bone marrow into damaged tissues will result in improved blood flow. If successful, this treatment could improve blood flow to the lower limb, reduce pain, and reduce the frequency of limb amputations.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

34 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Alabama

    Birmingham, Alabama, United States

  • Medical Center of South Arkansas

    El Dorado, Arkansas, United States

  • Usc Keck School of Medicine

    Los Angeles, California, United States

  • Florida Hospital - Vascular Institute of Central Florida

    Orlando, Florida, United States

  • Coastal Vascular & Interventional

    Pensacola, Florida, United States

  • Usf / Tampa General

    Tampa, Florida, United States

  • University of Illinois-Chicago

    Chicago, Illinois, United States

  • Cadence Health, Central Dupage Hospital

    Winfield, Illinois, United States

  • Ochsner Clinic

    New Orleans, Louisiana, United States

  • Maine Medical Ctr

    Portland, Maine, United States

  • Johns Hopkins Hospital

    Baltimore, Maryland, United States

  • Beth Israel Deaconess

    Boston, Massachusetts, United States

  • Tufts Medical Center

    Boston, Massachusetts, United States

  • Kansas City Vascular

    Kansas City, Missouri, United States

  • Mercy Hospital

    St Louis, Missouri, United States

  • Dartmouth Hitchcock Medical Ctr

    Lebanon, New Hampshire, United States

  • Cooper University Hospital

    Camden, New Jersey, United States

  • Holy Name Medical Center

    Teaneck, New Jersey, United States

  • North Shore-Long Island Jewish

    Lake Success, New York, United States

  • St. Luke'S Roosevelt

    New York, New York, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, United States

  • Wake Forest Baptist Health

    Winston-Salem, North Carolina, United States

  • University of Cincinnati

    Cincinnati, Ohio, United States

  • Regional Infectious Disease and Infusion Ctr

    Lima, Ohio, United States

  • University of Oklahoma

    Tulsa, Oklahoma, United States

  • Oregon Health Science University

    Portland, Oregon, United States

  • Rhode Island Hospital

    Providence, Rhode Island, United States

  • Roper St Francis Medical Center

    Charleston, South Carolina, United States

  • Greenville Health System

    Greenville, South Carolina, United States

  • University of Tennessee

    Knoxville, Tennessee, United States

  • Baylor Medical Ctr

    Dallas, Texas, United States

  • University of Texas - Houston Medical School

    Houston, Texas, United States

  • Peace Health Southwest Medical Center

    Vancouver, Washington, United States

  • Charleston Area Medical Center Institute

    Charleston, West Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 May 2011
Primary completion
31 Aug 2015
Completion
30 Nov 2015
Last update posted
15 Dec 2015
Registered enrollment
97
Registry id
NCT01245335

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.