Clinical trialNCT01262625TerminatedInterventional

Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations

SponsorAmerican College of RadiologyEnrollment1,050Angina EquivalentChest PainCoronary Artery DiseaseStable Angina Pectoris, CCS Class I to III

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This randomized, controlled, diagnostic, multicenter trial will compare two diagnostic imaging pathways--coronary computed tomography angiography (CCTA) and single photon emission tomography (SPECT) myocardial perfusion imaging (MPI)--to determine the incidence of major adverse coronary events (MACE), defined as myocardial infarction (MI) or cardiac-related death, and cross-over to revascularization. CCTA may be used to direct patients with symptoms of stable angina or angina equivalent to optimal medical therapy (OMT). The use of CCTA as a diagnostic tool for angina symptoms will be associated with no increase in MACE or revascularization, decreased cost, reduced risks (e.g., less radiation exposure), additional insights into alternate explanations of chest pain, and increased cost-effectiveness in comparison with use of SPECT MPI/invasive coronary angiography (ICA).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Arthur Stillman, MD, PhD
Division of Cardiothoracic Imaging, Emory University
Principal Investigator
clinicaltrials.gov ↗
Pamela K Woodard, MD
Mallinckrodt Institute of Radiology, Washington University of Medicine
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Atlantic Va Medical Center
Decatur, Georgia, United States
Henry Ford Hospital
Detroit, Michigan, United States
Salem Va Medical Center
Salem, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 May 2011
Primary completion: 26 Nov 2014
Completion: 28 Feb 2015
Last update posted: 26 Dec 2023
Registered enrollment: 1,050
Registry id: NCT01262625

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.