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Clinical trialNCT01278615TerminatedPhase 2Interventional

Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

SponsorNational Cancer Institute (NCI)Enrollment16Recurrent Adult Diffuse Large Cell Lymphoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II clinical trial is studying how well selumetinib works in treating patients with relapsed or refractory diffuse large B-cell lymphoma. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Northwestern University

    Chicago, Illinois, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, United States

  • Decatur Memorial Hospital

    Decatur, Illinois, United States

  • Northshore University Healthsystem-Evanston Hospital

    Evanston, Illinois, United States

  • Ingalls Memorial Hospital

    Harvey, Illinois, United States

  • Illinois Cancercare-Peoria

    Peoria, Illinois, United States

  • Southern Illinois University

    Springfield, Illinois, United States

  • Fort Wayne Medical Oncology and Hematology Inc-Parkview

    Fort Wayne, Indiana, United States

  • Indiana University/melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, United States

  • University of Maryland/greenebaum Cancer Center

    Baltimore, Maryland, United States

  • Tufts Medical Center

    Boston, Massachusetts, United States

  • University of Massachusetts Memorial Health Care

    Worcester, Massachusetts, United States

  • University of Michigan

    Ann Arbor, Michigan, United States

  • Saint John'S Mercy Medical Center

    St Louis, Missouri, United States

  • Weill Medical College of Cornell University

    New York, New York, United States

  • M D Anderson Cancer Center

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Dec 2010
Primary completion
28 Feb 2014
Completion
31 May 2014
Last update posted
3 Feb 2016
Registered enrollment
16
Registry id
NCT01278615

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.