Clinical trialNCT01296152CompletedPhase 2Interventional

Pharmacokinetic Interactions Between DMPA and LPV/r Among HIV-Infected Women

SponsorAdvancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsEnrollment25HIV-1 Infection

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study was done to look at the level of Depo-Provera, an injectable birth control, in the blood to see whether it is affected by the anti-HIV drug Kaletra (lopinavir/ritonavir \[LPV/r\]). It is not known whether taking Depo-Provera together with Kaletra changes the amount of Kaletra in blood. Therefore, this study also looked at the levels of HIV and Kaletra before and after receiving a shot of Depo-Provera. This study evaluated the safety of Depo-Provera and Kaletra when they are used together. In addition to what is stated above, this study also explored any effect of Depo-Provera on the immune system.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Amneris E Luque, M.D.
University of Rochester ACTG CRS
Study Chair
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Susan E Cohn, M.D., M.P.H.
Northwestern University CRS
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

San Juan Hospital Pr Nichd Crs (5031)
San Juan, Puerto Rico

United States

University of Southern California la (5048)
Los Angeles, California, United States
Children'S National Medical Center Washington Dc Nichd Crs (5015)
Washington D.C., District of Columbia, United States
Washington Hospital Center Nichd Crs (5023)
Washington D.C., District of Columbia, United States
South Florida Childrens Diagnostic & Treatment Cen (5055)
Fort Lauderdale, Florida, United States
Northwestern University Crs (2701)
Chicago, Illinois, United States
Rush University Cook County Hospital Chicago Nichd Crs (5083)
Chicago, Illinois, United States
Tulane University New Orleans Nichd Crs (5095)
New Orleans, Louisiana, United States
Univ. of Rochester Actg Crs (1101)
Rochester, New York, United States
Suny Stony Brook Nichd Crs (5040)
Stony Brook, New York, United States
Unc Aids Crs (3201)
Chapel Hill, North Carolina, United States
Univ. of Cincinnati Crs
Cincinnati, Ohio, United States
Univ. of Cincinnati Crs (2401)
Cincinnati, Ohio, United States
University of Washington Aids Crs (1401)
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Depo-medroxyprogesterone acetate

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 May 2011
Primary completion: 31 Oct 2012
Completion: 31 Oct 2012
Last update posted: 22 Dec 2015
Registered enrollment: 25
Registry id: NCT01296152

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.