Clinical trialNCT01353547RecruitingObservational

Genes and Environment in Multiple Sclerosis

SponsorColumbia UniversityEnrollment5,000Multiple Sclerosis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the research study is to identify the genetic, environmental and immune profiles that may increase a person's risk of developing multiple sclerosis (MS). While MS is not a disease caused by a single variation in genetic material (DNA), a single environmental factor, or a single malfunction in immune cells, there are genetic alterations, environmental exposures and immunologic factors that make the development of MS more likely. Obtaining information about who is at risk for MS will be beneficial in the future if the investigators can identify effective ways to prevent or slow down the progression of this disease.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Zongqi Xia, MD, PhD
University of Pittsburgh
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

National Institute of Neurological Disorders and Stroke
Bethesda, Maryland, United States
Daniel S Reich, MD, PhD
Recruiting
Brigham and Women'S Hospital
Boston, Massachusetts, United States
Terminated
Massachusetts General Hospital
Boston, Massachusetts, United States
Terminated
Columbia University Irving Center
New York, New York, United States
Philip L De Jager, MD, PhD
Recruiting
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
Zongqi Xia, MD, PhD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Oct 2017
Primary completion: 31 Oct 2040
Completion: 31 Oct 2040
Last update posted: 14 May 2026
Registered enrollment: 5,000
Registry id: NCT01353547

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.