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Clinical trialNCT01379469TerminatedPhase 2Interventional

Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency

SponsorWashington University School of MedicineEnrollment20Alpha-1-antitrypsin DeficiencyLiver Cirrhosis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The primary objective is to determine if the medication Carbamazepine, can be used as a therapy for patients with severe liver disease due to Alpha-1-Antitrypsin Deficiency .
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Washington University in St. Louis School of Medicine

    St Louis, Missouri, United States

  • Children'S Hospital of Pittsburgh, Upmc

    Pittsburgh, Pennsylvania, United States

  • University of Pittsburgh Medical Center, Presbyterian Hospital

    Pittsburgh, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Carbamazepine PlaceboDrug-Carbamazepine
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jan 2012
Primary completion
28 Feb 2017
Completion
28 Feb 2017
Last update posted
12 Oct 2021
Registered enrollment
20
Registry id
NCT01379469
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.