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Clinical trialNCT01408030CompletedPhase 2Interventional

North American Study of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)

SponsorJames GossageEnrollment123EpistaxisTelangiectasia, Hereditary Hemorrhagic
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the NOSE Study is to carefully examine the efficacy and safety of 3 nasal sprays (bevacizumab, estriol, and tranexamic acid), compared to placebo, for the treatment of HHT related nosebleeds.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California Los Angeles

    Los Angeles, California, United States

  • Georgia Regents University

    Augusta, Georgia, United States

  • Johns Hopkins University

    Baltimore, Maryland, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Oregon Health Sciences University

    Portland, Oregon, United States

  • University of Utah

    Salt Lake City, Utah, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Bevacizumab →EstriolSterile salineTranexamic acid →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2011
Primary completion
30 Sept 2014
Completion
30 Sept 2014
Last update posted
19 Oct 2018
Registered enrollment
123
Registry id
NCT01408030
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.