Clinical trialNCT01431391CompletedPhase 2Interventional

Sequencing of Sipuleucel-T and ADT in Men With Non-metastatic Prostate Cancer

SponsorDendreonEnrollment68Prostate CancerProstatic AdenocarcinomaProstatic Neoplasm

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The main purpose of this study was to determine whether ADT started before or after sipuleucel-T led to a better immune system response. This study also evaluated the safety of sipuleucel-T and ADT treatment, immune system responses over time, the characteristics of sipuleucel-T, and changes in prostate specific antigen (PSA) values over time.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Robert Israel, MD
Valeant Pharmaceuticals North America LLC
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Urology Center of Alabama
Homewood, Alabama, United States
University of California San Diego / Moores Cancer Center
La Jolla, California, United States
Keck Hospital of Usc
Los Angeles, California, United States
Lac + Usc Medical Center
Los Angeles, California, United States
Usc / Norris Comprehensive Cancer Center
Los Angeles, California, United States
the Urology Center of Colorado
Denver, Colorado, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, United States
Community Care Physicians, Pc
Albany, New York, United States
Nyoh Albany Cancer Center at Patroon Creek
Albany, New York, United States
Grand Strand Urology
Myrtle Beach, South Carolina, United States
Urology San Antonio Research
San Antonio, Texas, United States
Seattle Cancer Care Alliance
Seattle, Washington, United States
Virginia Mason Medical Center
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Leuprolide →Sipuleucel-T →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Sept 2011
Primary completion: 31 Dec 2014
Completion: 31 Dec 2014
Last update posted: 30 May 2017
Registered enrollment: 68
Registry id: NCT01431391

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.