Clinical trialNCT01437995CompletedPhase 4Interventional

Long-acting Beta Agonist Step Down Study

SponsorJohns Hopkins UniversityEnrollment459Asthma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is a 56-week, multi-center, blinded, randomized, double-masked parallel group comparative effectiveness study of approaches to stepping down therapy for patients with well-controlled asthma treated with combination ICS and LABA.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Linda Rogers, MD
NYU Langone Health
Principal Investigator
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Robert A Wise, MD
Johns Hopkins University
Study DirectorKOL profile →
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

19 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Arizona, Arizona Respiratory Center
Tucson, Arizona, United States
University of California, San Diego
San Diego, California, United States
National Jewish Health
Denver, Colorado, United States
Nemours Children'S Clinic
Jacksonville, Florida, United States
University of Miami/university of South Florida
Tampa, Florida, United States
the Illinois Consortium
Chicago, Illinois, United States
St. Vincent Healthcare
Indianapolis, Indiana, United States
St. Vincent Hospital and Health Care Center, Inc
Indianapolis, Indiana, United States
Louisiana State University Health Sciences Center, the Ernest N. Morial Asthma, Allergy and Respiratory Disease Center
New Orleans, Louisiana, United States
University of Missouri, Kansas City School of Medicine
Kansas City, Missouri, United States
Washington University/st. Louis University
St Louis, Missouri, United States
Hofstra North Shore-Lij School of Medicine
New Hyde Park, New York, United States
New York University School of Medicine
New York, New York, United States
Maria Fareri Children'S Hospital at Westchester Medical Center and New York Medical College
Valhalla, New York, United States
Duke University Medical Center
Durham, North Carolina, United States
the Ohio State University Medical Center
Columbus, Ohio, United States
Baylor College of Medicine
Houston, Texas, United States
Northern New England Consortium
Colchester, Vermont, United States
University of Virginia
Charlottesville, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Fluticasone DiskusFluticasone

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Mar 2012
Primary completion: 30 Sept 2015
Completion: 31 Oct 2015
Last update posted: 25 Apr 2017
Registered enrollment: 459
Registry id: NCT01437995

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.