Clinical trialNCT01440751CompletedPhase 4Interventional

Comparative Study of Ologen Collagen Matrix Versus Mitomycin-C in Glaucoma Filtering Surgery

SponsorAeon Astron Europe B.V.Enrollment99Glaucoma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The objective of this prospective randomised study is to compare the efficacy and safety of ologen CM (Collagen matrix) and Mitomycin-C (MMC) as adjuncts to filtration surgery in uncontrolled treated glaucoma cases, the efficacy being the primary objective and the safety being the secondary.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Angelo Tanna, MD
Northwestern Memorial Hospital
Study Director
clinicaltrials.gov ↗
David Godfrey, MD
Glaucoma Associates of Texas
Study Director
clinicaltrials.gov ↗
Michael Pro, MD
Wills Eye Institue
Study Director
clinicaltrials.gov ↗
Paul Sidoti, MD
New York Eye and Ear Infirmiry
Study Director
clinicaltrials.gov ↗
Robert Fechtner, MD
Institute of Ophthalmology and Visual Science
Study DirectorKOL profile →
clinicaltrials.gov ↗
Robert Ritch, MD
Robert Ritch, MD, LLC.
Principal Investigator
clinicaltrials.gov ↗
Steven Sarkisian, MD
Dean McGee Eye Institute
Study Director
clinicaltrials.gov ↗
Steven Vold, MD
Boozman-Hof Eye Clinic
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Voldvision-Holf Eye Clinic
Rogers, Arkansas, United States
Northwestern Memorial Hospital
Chicago, Illinois, United States
Institue of Ophthalmology and Visual Science
Newark, New Jersey, United States
Glaucoma Associates of New York
New York, New York, United States
New York Eye and Ear Infirmary
New York, New York, United States
Dean Mcgee Eye Institue
Oklahoma City, Oklahoma, United States
Wills Eye Institue
Philadelphia, Pennsylvania, United States
Glaucoma Associates of Texas
Dallas, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Use of Mitomycin-C in trabeculectomy

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Sept 2011
Primary completion: 31 Dec 2013
Completion: 31 Dec 2015
Last update posted: 1 Nov 2017
Registered enrollment: 99
Registry id: NCT01440751

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.