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Clinical trialNCT01531673CompletedPhase 2Interventional

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

SponsorVertex Pharmaceuticals IncorporatedEnrollment194Cystic Fibrosis
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

36 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Vertex Investigational Site

    Calgary, Alberta, Canada

  • Vertex Investigational Site

    Vancouver, British Columbia, Canada

  • Vertex Investigational Site

    Halifax, Nova Scotia, Canada

  • Vertex Investigational Site

    Toronto, Ontario, Canada

Germany
  • Vertex Investigational Site

    Erlangen, Bavaria, Germany

  • Vertex Investigational Site

    Frankfurt am Main, Hesse, Germany

  • Vertex Investigational Site

    Hanover, Lower Saxony, Germany

  • Vertex Investigational Site

    Cologne, North Rhine-Westphalia, Germany

  • Vertex Investigational Site

    Berlin, Germany

  • Vertex Investigational Site

    Bochum, Germany

  • Vertex Investigational Site

    Jena, Germany

  • Vertex Investigational Site

    Munich, Germany

United Kingdom
  • Vertex Investigational Site

    Cambridge, Cambridgeshire, United Kingdom

  • Vertex Investigational Site

    London, Greater London, United Kingdom

  • Vertex Investigational Site

    Manchester, Greater Manchester, United Kingdom

  • Vertex Investigational Site

    Southhampton, Hampshire, United Kingdom

  • Vertex Investigational Site

    Cardiff, Vale of Glamorgen, United Kingdom

United States
  • Vertex Investigational Site

    Birmingham, Alabama, United States

  • Vertex Investigational Site

    Oakland, California, United States

  • Vertex Investigational Site

    Boise, Idaho, United States

  • Vertex Investigational Site

    Chicago, Illinois, United States

  • Vertex Investigational Site

    Boston, Massachusetts, United States

  • Vertex Investigational Site

    Grand Rapids, Michigan, United States

  • Vertex Investigational Site

    Kansas City, Missouri, United States

  • Vertex Investigational Site

    Long Branch, New Jersey, United States

  • Vertex Investigational Site

    New Hyde Park, New York, United States

  • Vertex Investigational Site

    Chapel Hill, North Carolina, United States

  • Vertex Investigational Site

    Cincinnati, Ohio, United States

  • Vertex Investigational Site

    Columbus, Ohio, United States

  • Vertex Investigational Site

    Oklahoma City, Oklahoma, United States

  • Vertex Investigational Site

    Hershey, Pennsylvania, United States

  • Vertex Investigational Site

    Pittsburgh, Pennsylvania, United States

  • Vertex Investigational Site

    Charleston, South Carolina, United States

  • Vertex Investigational Site

    Salt Lake City, Utah, United States

  • Vertex Investigational Site

    Burlington, Vermont, United States

  • Vertex Investigational Site

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
29 Feb 2012
Primary completion
31 Mar 2014
Completion
31 Mar 2014
Last update posted
13 Apr 2018
Registered enrollment
194
Registry id
NCT01531673

Cross-registrations

EU-CTR / CTIS (EudraCT)2011-003821-93

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.