Clinical trialNCT01661634CompletedPhase 3Interventional

Efficacy and Safety of Ularitide for the Treatment of Acute Decompensated Heart Failure

SponsorCardiorentisEnrollment2,157Acute Decompensated Heart Failure

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate the efficacy and safety of a continuous intravenous (IV) ularitide infusion on the clinical status and outcome of patients with acute decompensated heart failure (ADHF).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Christopher O'Connor, MD
Principal Investigator
clinicaltrials.gov ↗
Milton Packer, MD
Study ChairKOL profile →
clinicaltrials.gov ↗
William F. Peacock, MD
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

163 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Argentina

Facility name not stated
Ciudad Autonoma, Buenos Aires, Argentina
Facility name not stated
Coronel Suárez, Buenos Aires, Argentina
Facility name not stated
La Plata, Buenos Aires, Argentina
Facility name not stated
Córdoba, Córdoba Province, Argentina
Facility name not stated
San Vicente, Córdoba Province, Argentina
Facility name not stated
Rosario, Santa Fe Province, Argentina
Facility name not stated
San Miguel de Tucumán, Tucumán Province, Argentina
Facility name not stated
Corrientes, Argentina
Facility name not stated
Córdoba, Argentina
Facility name not stated
Córdoba, Argentina
Facility name not stated
Córdoba, Argentina
Facility name not stated
Córdoba, Argentina
Facility name not stated
Córdoba, Argentina
Facility name not stated
San Miguel de Tucumán, Argentina
Facility name not stated
Santa Fe, Argentina
Facility name not stated
Santa Fe, Argentina

Belgium

Facility name not stated
Aalst, Belgium
Facility name not stated
Kortrijk, Belgium

Brazil

Facility name not stated
Goiânia, Goiás, Brazil
Facility name not stated
Porto Alegre, Rio Grande do Sul, Brazil
Facility name not stated
Campinas, São Paulo, Brazil
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São José do Rio Preto, São Paulo, Brazil
Facility name not stated
São Paulo, São Paulo, Brazil

Canada

Facility name not stated
Halifax, Nova Scotia, Canada
Facility name not stated
Montreal, Quebec, Canada
Facility name not stated
Montreal, Quebec, Canada

Czechia

Facility name not stated
Brno, Czechia
Facility name not stated
Brno, Czechia
Facility name not stated
Frýdek-Místek, Czechia
Facility name not stated
Hradec Králové, Czechia
Facility name not stated
Olomouc, Czechia
Facility name not stated
Prague, Czechia
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Prague, Czechia
Facility name not stated
Prague, Czechia
Facility name not stated
Prague, Czechia
Facility name not stated
Prague, Czechia
Facility name not stated
Znojmo, Czechia

Estonia

Facility name not stated
Tallinn, Estonia
Facility name not stated
Tallinn, Estonia

Finland

Facility name not stated
Espoo, Finland

123 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboUlaritide

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2012
Primary completion: 30 Nov 2015
Completion: 31 Mar 2016
Last update posted: 23 Oct 2018
Registered enrollment: 2,157
Registry id: NCT01661634

Cross-registrations

EU-CTR / CTIS (EudraCT)2010-024249-59

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.