Clinical trialNCT01687153CompletedObservational

A Study of Brain Aging in Vietnam War Veterans

SponsorUniversity of Southern CaliforniaEnrollment289Alzheimer's DiseaseMild Cognitive ImpairmentPost Traumatic Stress DisorderTraumatic Brain Injury

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) are common combat related problems and may be associated with a greater risk of Alzheimer's disease (AD). The purpose of this study is to examine the possible connections between TBI and PTSD, and the signs and symptoms of AD on Veterans as they age. The information collected will help to learn more about how these injuries may affect Veterans of the Vietnam War as they grow older, as well as Veterans of the current wars in Iraq and Afghanistan, who also have these types of combat related injuries.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Michael W. Weiner, MD
University of California, San Francisco
Study Director
clinicaltrials.gov ↗
Paul Aisen, MD
USC Alzheimer's Therapeutic Research Institute (ATRI)
Principal Investigator
clinicaltrials.gov ↗
Ronald Petersen, MD, PhD
Mayo Clinic
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

19 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Banner Sun Health Research Institute
Sun City, Arizona, United States
University of California, Irvine
Irvine, California, United States
University of California, San Diego
La Jolla, California, United States
University of Southern California
Los Angeles, California, United States
Va Palo Alto Hsc / Stanford School of Medicine
Palo Alto, California, United States
University of California, San Francisco
San Francisco, California, United States
Georgetown University
Washington D.C., District of Columbia, United States
Howard University
Washington D.C., District of Columbia, United States
Wien Center for Clinical Research
Miami Beach, Florida, United States
Premiere Research Institute
West Palm Beach, Florida, United States
Rush University Medical Center
Chicago, Illinois, United States
Brigham and Women'S Hospital
Boston, Massachusetts, United States
Columbia University
New York, New York, United States
Cornell Medical Center
New York, New York, United States
University of Rochester Medical Center
Rochester, New York, United States
Duke University Medical Center
Durham, North Carolina, United States
Roper St Francis Healthcare
Charleston, South Carolina, United States
U of Wa / Va Puget Sound Alzheimer'S Disease Research Center
Seattle, Washington, United States
University of Wisconsin
Madison, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2012
Primary completion: 21 Sept 2021
Completion: 21 Sept 2021
Last update posted: 29 Nov 2021
Registered enrollment: 289
Registry id: NCT01687153

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.