Clinical trialNCT01725269TerminatedPhase 2Interventional

Long-term Study of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension Who Completed AIR001-CS05

SponsorAires Pharmaceuticals, Inc.Enrollment17Pulmonary Arterial Hypertension

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The AIR001-CS05 study evaluated the safety and efficacy (effectiveness) of AIR001 over 16 weeks in subjects who have PAH. The purpose of the AIR001-CS06 study is to evaluate the intermediate / long-term safety of AIR001 in subjects who have completed the AIR001-CS05 study. Assessments to evaluate the effectiveness of the study drug will include measurements of exercise ability and evaluations of PAH disease symptoms.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Adaani E Frost, M.D.
Baylor College of Medicine
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

25 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

St. Vincent'S Hospital
Darlinghurst, New South Wales, Australia
the Prince Charles Hospital
Chermside, Queensland, Australia
Royal Hobart Hospital
Hobart, Tasmania, Australia
the Alfred Hospital
Melbourne, Victoria, Australia

Hungary

Gottsegen Gyorgy Hungarian
Budapest, Hungary
Semmelweis University
Budapest, Hungary
University of Debrecen
Debrecen, Hungary
University of Szeged
Szeged, Hungary

United States

Ucsd Medical Center
La Jolla, California, United States
Ucla Medical Center
Torrance, California, United States
University of Colorado Denver
Aurora, Colorado, United States
Kentuckiana Pulmonary Associates
Louisville, Kentucky, United States
University of Maryland Medical Center
Baltimore, Maryland, United States
Boston University School of Medicine
Boston, Massachusetts, United States
Brigham and Women'S Hospital
Boston, Massachusetts, United States
Tufts Medical Center
Boston, Massachusetts, United States
Washington University School of Medicine
St Louis, Missouri, United States
Duke University Medical Center
Durham, North Carolina, United States
University of Cincinnati
Cincinnati, Ohio, United States
the Ohio State University Medical Center
Columbus, Ohio, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
University of Texas Southwestern Medical Center
Dallas, Texas, United States
Adaani Frost, M.D.
Houston, Texas, United States
Inova Fairfax Hospital
Falls Church, Virginia, United States
Aurora St. Luke'S Medical Center
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AIR001

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Mar 2013
Primary completion: 30 Apr 2014
Completion: 30 Apr 2014
Last update posted: 9 Apr 2014
Registered enrollment: 17
Registry id: NCT01725269

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.