Clinical trialNCT01756833CompletedPhase 2Interventional

Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial

SponsorUniversity of Maryland, BaltimoreEnrollment261Aneurysm

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The primary aim of this study is to determine if doxycycline (100 mg bid) will inhibit (by at least 40%) the increase in greatest transverse diameter of small abdominal aortic aneurysms (3.5-5.0 cm in men, 3.5-4.5 cm in women) over a 24-month period of observation in comparison to a placebo-treated control group.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Bernard T Baxter, MD
University of Nebraska
Principal Investigator
clinicaltrials.gov ↗
John Curci, MD
Vanderbilt University
Principal Investigator
clinicaltrials.gov ↗
Jonathan Matsumura, MD
University of Wisconsin Medical Center
Principal Investigator
clinicaltrials.gov ↗
Michael L Terrin, MD
University of Maryland, Baltimore
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

22 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Carondelet Heart & Vascular Institute
Tucson, Arizona, United States
University of Arizona Medical Center
Tucson, Arizona, United States
University of Southern California
Los Angeles, California, United States
Stanford University
Stanford, California, United States
Miami Cardiac and Vascular Institute
Miami, Florida, United States
University of South Florida Health Center
Tampa, Florida, United States
Northwestern University Memorial Hospital
Chicago, Illinois, United States
University of Maryland Medical Center
Baltimore, Maryland, United States
Beth Israel Deaconness Medical Center
Boston, Massachusetts, United States
University of Michigan Medical Center
Ann Arbor, Michigan, United States
Mclaren Northern Michigan
Petoskey, Michigan, United States
Washington University School of Medicine
St Louis, Missouri, United States
Omaha Vamc
Omaha, Nebraska, United States
University of Nebraska Medical Center
Omaha, Nebraska, United States
Columbia University Medical Center
New York, New York, United States
Oregon Health Sciences University
Portland, Oregon, United States
Portland Vamc
Portland, Oregon, United States
Geisinger Medical Center
Danville, Pennsylvania, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
University of Texas Southwestern Medical Center
Dallas, Texas, United States
University of Utah Health Sciences Center
Salt Lake City, Utah, United States
Utah Vamc
Salt Lake City, Utah, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Doxycycline →Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 May 2013
Primary completion: 23 Jul 2019
Completion: 23 Jul 2019
Last update posted: 26 Nov 2021
Registered enrollment: 261
Registry id: NCT01756833

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.