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Clinical trialNCT01802281CompletedInterventional

Study of Uterine Prolapse Procedures - Randomized Trial

SponsorNICHD Pelvic Floor Disorders NetworkEnrollment183Uterovaginal Prolapse
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The primary purpose of this randomized clinical trial is to compare the effectiveness and safety of two transvaginal apical suspension strategies for uterovaginal prolapse: a mesh augmented hysteropexy versus vaginal hysterectomy and uterosacral ligament suspension (USLS). The primary aim is to determine whether treatment success in women who undergo the above strategies differ at time points through 3 years. A supplemental study investigates anterior vaginal wall movement resulting from descent or rotation of the vaginal apex and/or anterior vaginal elongation, in women in both of the study arms of SUPeR.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Anthony G Visco, MD

    Duke University, Duke Division of Urogynecology and Reconstructive Pelvic Surgery

    Principal Investigator
    clinicaltrials.gov ↗
  • Charles R Rardin, MD

    Brown/ Women and Infants Hospital of Rhode Island, Center for Women's Pelvic Medicine and Reconstructive Surgery

    Principal Investigator
    clinicaltrials.gov ↗
  • Charles W Nager, MD

    University of California at San Diego, UCSD Women's Pelvic Medicine Center

    Principal Investigator
    clinicaltrials.gov ↗
  • Halina M Zyczynski, MD

    Magee-Women's Hospital, Department of Obstetrics and Gynecology

    Principal Investigator
    clinicaltrials.gov ↗
  • Heidi Harvie, MD

    University of Pennsylvania

    Principal Investigator
    clinicaltrials.gov ↗
  • Holly E Richter, PhD, MD

    University of Alabama at Birmingham, Department of Obstetrics and Gynecology

    Principal Investigator
    clinicaltrials.gov ↗
  • Kate Meriwether, MD

    University of New Mexico Health Sciences Center, Department of Obstetrics and Gynecology

    Principal Investigator
    clinicaltrials.gov ↗
  • Marie Paraiso, MD

    Cleveland Clinic, Department OB/GYN

    Principal Investigator
    clinicaltrials.gov ↗
  • Sonia Thomas, DrPH

    RTI International

    Principal Investigator
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Alabama at Birmingham, Department of Obstetrics and Gynecology

    Birmingham, Alabama, United States

  • University of California at San Diego, Ucsd Women'S Pelvic Medicine Center

    La Jolla, California, United States

  • University of New Mexico Health Sciences Center, Department of Obstetrics and Gynecology

    Albuquerque, New Mexico, United States

  • Duke University, Duke Division of Urogynecology and Reconstructive Pelvic Surgery

    Durham, North Carolina, United States

  • Cleveland Clinic, Department Ob/gyn

    Cleveland, Ohio, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Magee-Women'S Hospital, Department of Obstetrics and Gynecology

    Pittsburgh, Pennsylvania, United States

  • Brown/ Women and Infants Hospital of Rhode Island, Center for Women'S Pelvic Medicine and Reconstructive Surgery

    Providence, Rhode Island, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Apr 2013
Primary completion
31 Jul 2023
Completion
7 Mar 2025
Last update posted
26 Aug 2025
Registered enrollment
183
Registry id
NCT01802281
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.