Clinical trialNCT01807897CompletedPhase 4Interventional

Oxygen Versus PAP for Sleep Apnea in Heart Failure

SponsorVA Office of Research and DevelopmentEnrollment74Heart FailureSleep Apnea Syndromes

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to compare three treatment modalities for central, or mixed obstructive and central, sleep apnea in patients with chronic heart failure and reduced ejection fraction. The modalities to be tested are nocturnal supplemental oxygen (NSO) and continuous positive airway pressure (CPAP). The main outcome measures will be left ventricular ejection fraction on echocardiogram and peak oxygen consumption on cardiopulmonary exercise testing.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Daniel J Gottlieb, MD MPH
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Va Connecticut Healthcare System West Haven Campus, West Haven, Ct
West Haven, Connecticut, United States
Va Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, Ma
Boston, Massachusetts, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 23 Jun 2014
Primary completion: 30 Jun 2020
Completion: 30 Jun 2020
Last update posted: 25 Jan 2023
Registered enrollment: 74
Registry id: NCT01807897

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.