FindMyKOL
Clinical trialNCT01811212CompletedPhase 2Interventional

Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer

SponsorNational Cancer Institute (NCI)Enrollment25Poorly Differentiated Thyroid Gland CarcinomaRecurrent Thyroid Gland CarcinomaStage I Thyroid Gland Follicular CarcinomaStage I Thyroid Gland Papillary CarcinomaStage II Thyroid Gland Follicular CarcinomaStage II Thyroid Gland Papillary Carcinoma+10 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II trial studies how well cabozantinib-s-malate works in treating patients with thyroid cancer that does not respond to treatment. Cabozantinib-s-malate may stop the growth of thyroid cancer by blocking some of the enzymes needed for cell growth. Cabozantinib-s-malate may also stop the growth of thyroid cancer by blocking blood flow to the tumor.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Medstar Georgetown University Hospital

    Washington D.C., District of Columbia, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, United States

  • Mayo Clinic

    Rochester, Minnesota, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, United States

  • M D Anderson Cancer Center

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
8 May 2013
Primary completion
13 Jul 2015
Completion
9 Oct 2017
Last update posted
3 Apr 2018
Registered enrollment
25
Registry id
NCT01811212

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.