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Clinical trialNCT01817075CompletedPhase 3Interventional

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

SponsorChildren's Oncology GroupEnrollment177Bacterial InfectionBenign NeoplasmMalignant NeoplasmMethicillin-Resistant Staphylococcus Aureus InfectionMyeloid NeoplasmRecurrent Childhood Acute Lymphoblastic Leukemia+1 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This randomized phase III trial studies chlorhexidine gluconate cleansing to see how well it works compared to control cleansing in preventing central line associated bloodstream infection and acquisition of multi-drug resistant organisms in younger patients with cancer or undergoing donor stem cell transplant. Chlorhexidine gluconate may help reduce bloodstream infections and bacterial infections associated with the central line.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

59 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Children'S Hospital

    London, Ontario, Canada

  • Children'S Hospital of Eastern Ontario

    Ottawa, Ontario, Canada

  • Hospital for Sick Children

    Toronto, Ontario, Canada

  • the Montreal Children'S Hospital of the Muhc

    Montreal, Quebec, Canada

Puerto Rico
  • San Jorge Children'S Hospital

    San Juan, Puerto Rico

  • University Pediatric Hospital

    San Juan, Puerto Rico

United States
  • City of Hope Comprehensive Cancer Center

    Duarte, California, United States

  • Miller Children'S and Women'S Hospital Long Beach

    Long Beach, California, United States

  • Children'S Hospital Los Angeles

    Los Angeles, California, United States

  • Valley Children'S Hospital

    Madera, California, United States

  • Children'S Hospital and Research Center at Oakland

    Oakland, California, United States

  • Children'S Hospital of Orange County

    Orange, California, United States

  • Ucsf Medical Center-Mission Bay

    San Francisco, California, United States

  • Ucsf Medical Center-Parnassus

    San Francisco, California, United States

  • Lundquist Institute for Biomedical Innovation at Harbor-Ucla Medical Center

    Torrance, California, United States

  • Connecticut Children'S Medical Center

    Hartford, Connecticut, United States

  • Yale University

    New Haven, Connecticut, United States

  • Alfred I Dupont Hospital for Children

    Wilmington, Delaware, United States

  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

  • Nemours Children'S Clinic-Jacksonville

    Jacksonville, Florida, United States

  • Nemours Children'S Hospital

    Orlando, Florida, United States

  • Nemours Children'S Clinic - Pensacola

    Pensacola, Florida, United States

  • Johns Hopkins All Children'S Hospital

    St. Petersburg, Florida, United States

  • Tampa General Hospital

    Tampa, Florida, United States

  • Children'S Healthcare of Atlanta - Egleston

    Atlanta, Georgia, United States

  • University of Illinois

    Chicago, Illinois, United States

  • Children'S Hospital New Orleans

    New Orleans, Louisiana, United States

  • Ochsner Medical Center Jefferson

    New Orleans, Louisiana, United States

  • Eastern Maine Medical Center

    Bangor, Maine, United States

  • Johns Hopkins University/sidney Kimmel Cancer Center

    Baltimore, Maryland, United States

  • Sinai Hospital of Baltimore

    Baltimore, Maryland, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, United States

  • Wayne State University/karmanos Cancer Institute

    Detroit, Michigan, United States

  • Children'S Mercy Hospitals and Clinics

    Kansas City, Missouri, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, United States

  • the Steven and Alexandra Cohen Children'S Medical Center of New York

    New Hyde Park, New York, United States

  • Nyp/columbia University Medical Center/herbert Irving Comprehensive Cancer Center

    New York, New York, United States

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, United States

  • New York Medical College

    Valhalla, New York, United States

19 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
4 Nov 2013
Primary completion
31 Mar 2019
Completion
31 Mar 2020
Last update posted
22 Jun 2021
Registered enrollment
177
Registry id
NCT01817075

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.