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Clinical trialNCT01971658CompletedPhase 3Interventional

Efficacy Study Comparing Velcade Dexamethasone Thalidomide Versus Velcade Cyclophosphamide Dexamethasone as Induction Treatment in the Initial Management of Multiple Myeloma (IFM2013-04)

SponsorNantes University HospitalEnrollment358Multiple Myeloma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a phase III, multicenter, prospective with a clinical benefit, open-label and randomized study to compare two different treatments : Velcade (Bortezomib) Thalidomide Dexamethasone (VTD) versus Velcade (Bortezomib) Cyclophosphamide Dexamethasone (VCD) as an Induction Treatment prior to Autologous Stem Cell Transplantation in patients with Newly Diagnosed Multiple Myeloma. Eligible patients will be randomized into 2 treatment arms. Each patient will receive 4 consecutive 21 day cycles of an induction treatment with either VTD or VCD.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

63 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

France
  • Chu Angers

    Angers, Angers, France

  • Hôpital Pitié-Salpétrière

    Paris, Paris, France

  • Centre Hospitalier de la Région D'Annecy

    Annecy, Pringy, France

  • Chru Hôpital Sud

    Amiens, France

  • Centre Hospitalier Argenteuil

    Argenteuil, France

  • Centre Hospitalier H.Duffaut

    Avignon, France

  • Centre Hospitalier de la Côte Basque

    Bayonne, France

  • Chru de Besançon

    Besançon, France

  • Hôpital Avicenne

    Bobigny, France

  • Polyclinique Bordeaux Nord Aquitaine

    Bordeaux, France

  • Centre Hospitalier Pierre Oudot

    Bourgoin, France

  • Hôpital A.Morvan

    Brest, France

  • Chu Caen Côte de Nacre

    Caen, France

  • Ch René Dubos

    Cergy-Pontoise, France

  • Centre Hospitalier William Morey

    Chalon/saone, France

  • Hôpital D'Instruction Des Armées Percy

    Clamart, France

  • Chu D'Estaing

    Clermont-Ferrand, France

  • Hôpitaux Civils de Colmar

    Colmar, France

  • Centre Hospitalier Sud Francilien

    Corbeil-Essonnes, France

  • Chu Henri Mondor

    Créteil, France

  • Chru Dijon

    Dijon, France

  • Centre Hospitalier Général

    Dunkirk, France

  • Chru - Hôpital A.Michallon

    Grenoble, France

  • Centre Hospitalier Départemental Vendée

    La Roche-sur-Yon, France

  • Hôpital Louis Pasteur

    Le Coudray, France

  • Ch Le Mans

    Le Mans, France

  • Centre Jean Bernard

    Le Mans, France

  • Chru - Hôpital Claude Huriez

    Lille, France

  • Hopital Saint Vincent de Paul

    Lille, France

  • Chu de Limoges

    Limoges, France

  • Hôpital Du Scorff

    Lorient, France

  • Centre Léon Bérard

    Lyon, France

  • Institut Paoli Calmettes

    Marseille, France

  • Centre Hospitalier de Meaux

    Meaux, France

  • Chr Metz Thionville

    Metz, France

  • Centre Hospitalier Intercommunale Meulan Les Mureaux

    Meulan-en-Yvelines, France

  • Hopital E Muller

    Mulhouse, France

  • Nantes University Hospital

    Nantes, France

  • Hôpital de L'Archet 1

    Nice, France

  • Groupe Hospitalo-Universitaire Carémeau

    Nîmes, France

23 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Oct 2013
Primary completion
31 Aug 2015
Completion
31 Aug 2015
Last update posted
7 Oct 2015
Registered enrollment
358
Registry id
NCT01971658

Cross-registrations

EU-CTR / CTIS (EudraCT)2013-003174-27

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.