Clinical trialNCT01979406CompletedPhase 1Interventional

A Phase 1 Ascending Dose Study to Assess the Safety and Immunogenicity of Adenovirus Anthrax Vector Candidate Vaccines

SponsorEmergent BioSolutionsEnrollment120Anthrax Infection

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate 2 vaccine candidates against anthrax compared to the positive (vaccine) control as studied in normal healthy volunteers.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Jakub Simon, MD
Emergent BioSolutions
Study Director
clinicaltrials.gov ↗
Marc Gurwith, MD
Emergent BioSolutions
Principal Investigator
clinicaltrials.gov ↗
Mo Elsafy, MD, MSc
National Institutes of Health (NIH)
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

the Center for Pharmaceutical Research
Kansas City, Kansas, United States
Walter Reed Army Institute for Research
Silver Spring, Maryland, United States
St. Louis University
St Louis, Missouri, United States
Coastal Carolina Research Center
Mt. Pleasant, South Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AVAAd4-PA-1Ad4-PA-GPI-1

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Nov 2013
Primary completion: 31 Oct 2014
Completion: 30 Sept 2015
Last update posted: 18 Mar 2024
Registered enrollment: 120
Registry id: NCT01979406

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.