Clinical trialNCT02040714Enrolling, by, invitationObservational

Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease

SponsorTexas Scottish Rite Hospital for ChildrenEnrollment1,500Legg Calve Perthes Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Legg-Calvé-Perthes disease is a childhood hip disorder which is common enough to be a significant public health problem (affects 1 in 740 boys between ages 0-14), but uncommon enough to have a sufficient number of patients from a single institution to perform a definitive prospective study comparing the results of current treatments. The present study will establish a database of prospectively identified patients with Legg-Calvé-Perthes (LCP) Disease and collect information regarding their presentation, treatment, and outcomes in the course of receiving currently available treatments. This study seeks to compare the outcomes of current treatments in the management of different age groups (ages 1-6, 6-8, 8-11, \>11) of patients with Perthes disease at two- and five-year followup and at skeletal maturity. For each age group, two to three common treatment regimens currently used by practicing pediatric orthopaedic surgeons will be compared. The intervention a patient receives is determined through physician treatment expertise, and is not pre-determined by the study.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Harry KW Kim, MD, MS
Texas Scottish Rite Hospital for Children
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

46 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Women and Children'S Hospital of Adelaide
Adelaide, South Australia, Australia

Brazil

Universidade de São Paulo
São Paulo, Brazil

Canada

Alberta Children'S Hospital, Division of Paediatric Surgery
Calgary, Alberta, Canada
British Columbia Children'S Hospital
Vancouver, British Columbia, Canada

China

Tianjin Hospital Pediatric Orthopedics
Tianjin, China

Germany

Children'S Hospital Hamburg-Altona
Hamburg, Germany
Hospital of Schleswig-Holstein
Lübeck, Germany
University Hospital of Schleswig-Holstein (campus Lubeck)
Lübeck, Germany

India

Kasturba Medical College (kmc), Manipal
Udupi, Karnataka, India

Ireland

Children'S Health Ireland at Temple Street
Dublin, Ireland

Norway

Oslo University Hospital
Oslo, Norway

Poland

Medical University of Lodz
Lodz, Poland

Puerto Rico

San Jorge Children'S Hospital
San Juan, Puerto Rico

Spain

Hospital Infantil Universitario Nino Jesus
Madrid, Spain

Sweden

Uppsala University
Uppsala, Sweden

Switzerland

Centre Hopsitalier Universitaire Vaudois
Lausanne, Switzerland

United Kingdom

Alder Hey Children'S Hosopital (university of Oxford)
Liverpool, United Kingdom
Southampton Children'S Hospital
Southampton, United Kingdom

United States

Children'S Hospital of Alabama
Birmingham, Alabama, United States
Children'S Hospital of Los Angeles
Los Angeles, California, United States
Kaiser Permanente Hospital
Los Angeles, California, United States
Rady Children'S Hospital California
San Diego, California, United States
Ucsf Benioff Children'S Hospitals
San Francisco, California, United States
Children'S Hospital Colorado
Aurora, Colorado, United States
Connecticut Children'S Medical Center
Hartford, Connecticut, United States
Alfred I. Dupont Hospital for Children of the Nemours Foundation
Wilmington, Delaware, United States
Children'S National Medical Center
Washington D.C., District of Columbia, United States
Children'S Orthopaedics of Atlanta
Atlanta, Georgia, United States
Ann & Robert H. Lurie Children'S Hospital of Chicago
Chicago, Illinois, United States
Johns Hopkins
Baltimore, Maryland, United States
Children'S Hospital Boston
Boston, Massachusetts, United States
Mayo Clinic
Rochester, Minnesota, United States
Gillette Children'S Specialty Healthcare
Saint Paul, Minnesota, United States
Nyu Langone/hospital for Joint Disease
New York, New York, United States
New York Presbyterian Hospital (columbia Campus)
New York, New York, United States
Children'S Hospital at Montefiore
The Bronx, New York, United States
Orthocarolina
Charlotte, North Carolina, United States
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Nationwide Children'S Hospital
Columbus, Ohio, United States
Oklahoma University Health Science Center
Oklahoma City, Oklahoma, United States

6 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2012
Primary completion: 30 Sept 2032
Completion: 30 Sept 2032
Last update posted: 6 May 2025
Registered enrollment: 1,500
Registry id: NCT02040714

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.