Clinical trialNCT02061436RecruitingObservational

Prospective Global Registry for the Study of Chronic Total Occlusion Intervention

SponsorMinneapolis Heart Institute FoundationEnrollment2,000Coronary Artery Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) is increasingly being performed in patients with advanced coronary artery disease, but there is limited information on the techniques utilized and the procedural outcomes. The goal of this multicenter, investigator initiated registry is to collect information on treatment strategies and outcomes of consecutive patients undergoing CTO PCI among various participating centers. The information collected will be used to determine the frequency of CTO PCI performed at the participating sites and examine the procedural strategies utilized, and the procedural (both immediate and during follow-up) outcomes.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Emmanouil S Brilakis, MD, PhD
Minneapolis Heart Institute Foundation
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

48 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

St. Boniface General Hospital
Winnipeg, Manitoba, Canada
Recruiting

Egypt

Aswan Heart Centre
Aswān, Egypt
Recruiting

Greece

Korgialeneio-Benakeio Hellenic Red Cross General Hospital of Athens
Athens, Attica, Greece
Michalis Koutouzis, MDYiannis Tsiafoutis, MDZenon Kuriakidis, MD
Recruiting
Henry Hunant Hospital Center
Athens, Greece
Recruiting

Lebanon

St. George Hospital University Medical Center
Beirut, Lebanon
Recruiting

Russia

Meshalkin Novosibirsk Research Institute
Novosibirsk, Novosibirsk Oblast, Russia
Oleg Krestyaninov, MD
Recruiting

United States

Banner Samaritan Health Center
Phoenix, Arizona, United States
Completed
Little Rock Va Medical Center
Little Rock, Arkansas, United States
Barry Uretsky, MD
Recruiting
San Diego Vamc and University of California
San Diego, California, United States
Ehtisham Mahmud, MDMitul Patel, MD
Recruiting
Torrance Memorial Medical Center
Torrance, California, United States
Active, not recruiting
Medical Center of the Rockies
Loveland, Colorado, United States
Anthony Doing, MDPhil Dattilo, MD
Recruiting
Memorial Hospital
Jacksonville, Florida, United States
Recruiting
Emory University Hospital- Emory Heart and Vascular Center
Atlanta, Georgia, United States
Recruiting
Piedmont Heart Institute
Atlanta, Georgia, United States
Active, not recruiting
Wellstar Health System
Marietta, Georgia, United States
Recruiting
Northwestern Bluhm Cardiovascular Institute
Chicago, Illinois, United States
Active, not recruiting
St. Vincent Heart Center
Indianapolis, Indiana, United States
Recruiting
Tulane University Heart and Vascular Institute
New Orleans, Louisiana, United States
Nidal Abi Rafeh, MDOwen Mogabgab, MD
Recruiting
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Robert W Yeh, MD, MBA
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Farouc Jaffer, MD, PhD
Recruiting
Henry Ford Medical Center
Detroit, Michigan, United States
Khaldoon Alaswad, MD
Recruiting
Minneapolis Heart Institute
Minneapolis, Minnesota, United States
Emmanouil S Brilakis, MD, PhD →Nicholas M Burke, MD
Recruiting
Minneapolis Va Healthcare System and University of Minnesota
Minneapolis, Minnesota, United States
Santiago Garcia, MD
Recruiting
Mid America Heart Institute
Kansas City, Missouri, United States
Active, not recruiting
Maimonides Medical Center
Brooklyn, New York, United States
Recruiting
Trinity Medical Wny
Buffalo, New York, United States
Recruiting
Columbia University
New York, New York, United States
Ajay J Kirtane, MDDimitri Karmpaliotis, MDJeffrey W Moses, MDManish A Parikh, MDZiad A Ali, MD, DPhil
Recruiting
Carolina East Medical Center
New Bern, North Carolina, United States
Alex R Kirby, MDDavid Jessup, MDMatt Grove, MD
Recruiting
the Christ Hospital Ohio Heart & Vascular
Cincinnati, Ohio, United States
Recruiting
Cleveland Clinic
Cleveland, Ohio, United States
Recruiting
University Hospitals (uh) Case Western Reserve University
Cleveland, Ohio, United States
Recruiting
Kettering Health Network
Kettering, Ohio, United States
Recruiting
Oklahoma City Va Medical Center
Oklahoma City, Oklahoma, United States
Recruiting
Oklahoma Heart Institute at Hillcrest Medical Center
Tulsa, Oklahoma, United States
Recruiting
Providence Heart & Vascular Institute
Portland, Oregon, United States
Recruiting
University of Pittsburgh Medical Center Presbyterian
Pittsburgh, Pennsylvania, United States
Catalin Toma, MDConrad AJ Smith, MD
Recruiting
Wellspan Heart & Vascular
York, Pennsylvania, United States
Recruiting
Tristar Centennial Medical Center
Nashville, Tennessee, United States
Recruiting
Baylor Heart and Vascular Hospital
Dallas, Texas, United States
James Choi, MD
Recruiting
University of Texas Southwestern Medical Center
Dallas, Texas, United States
Emmanouil S Brilakis, MD, PhD →
Recruiting

8 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jan 2012
Primary completion: 31 Jan 2030
Completion: 31 Jan 2030
Last update posted: 19 Aug 2026
Registered enrollment: 2,000
Registry id: NCT02061436

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.