Clinical trialNCT02082353UnknownObservational

Patients Treated for Chronic Granulomatous Disease (CGD) Since 1995

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment1,480Granulomatous Disease, Chronic

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Chronic granulomatous disease (CGD) is an inherited immune system abnormality in which bone marrow transplantation (BMT) has been shown to be curative. However the risks of transplantation are high and not all patients with CGD may need to undergo this high risk procedure. This study will determine the long term medical condition and daily functioning of participants with CGD after a transplant and if possible, compare these results to participants who do not undergo a transplant.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Donald B. Kohn, MD
University of California, Los Angeles
Principal Investigator
clinicaltrials.gov ↗
Jennifer M. Puck, MD
University of California, San Francisco
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

44 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Alberta Children'S Hospital
Calgary, Alberta, Canada
British Columbia Children'S Hospital
Vancouver, British Columbia, Canada
Cancer Care Manitoba
Winnipeg, Manitoba, Canada
the Hospital for Sick Children
Toronto, Ontario, Canada
Chu St. Justine
Montreal, Quebec, Canada

United States

University of Alabama at Birmingham
Birmingham, Alabama, United States
Phoenix Children'S Hospital
Phoenix, Arizona, United States
Children'S Hospital Los Angeles
Los Angeles, California, United States
Ucla
Los Angeles, California, United States
Lucile Salter Packard Children'S Hospital at Stanford
Palo Alto, California, United States
University of California (ucsf) Benioff Children'S Hospital
San Francisco, California, United States
Children'S Hospital Colorado
Aurora, Colorado, United States
Alfred I. Dupont Hospital for Children/nemours
Wilmington, Delaware, United States
Children'S National Medical Center, Washington Dc
Washington D.C., District of Columbia, United States
Johns Hopkins All Children'S Hospital - St. Petersburg, Fl
St. Petersburg, Florida, United States
Children'S Healthcare of Atlanta, Emory University
Atlanta, Georgia, United States
Ann & Robert H. Lurie Children'S Hospital of Chicago
Chicago, Illinois, United States
Children'S Hospital of New Orleans at Lsuhsc
New Orleans, Louisiana, United States
Nih Clinical Center Genetic Immunotherapy Section
Bethesda, Maryland, United States
Children'S Hospital Boston
Boston, Massachusetts, United States
University of Michigan Health System
Ann Arbor, Michigan, United States
University of Minnesota Medical Center
Minneapolis, Minnesota, United States
Mayo Clinic Hospital
Rochester, Minnesota, United States
Cardinal Glennon Children'S Hospital/ St. Louis University
St Louis, Missouri, United States
Washington University/ St.Louis Children'S Hospital
St Louis, Missouri, United States
Hackensack University Medical Center
Hackensack, New Jersey, United States
Memorial Sloan-Kettering Cancer Center
New York, New York, United States
University of Rochester Medical Center/ Golisano Children'S Hospital
Rochester, New York, United States
New York Medical College, Maria Fareri Children'S Hospital
Valhalla, New York, United States
Duke University
Durham, North Carolina, United States
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Rainbow Babies/ University Hospitals Case Medical Center
Cleveland, Ohio, United States
Nationwide Children'S Hospital
Columbus, Ohio, United States
Oregon Health and Science University
Portland, Oregon, United States
the Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Children'S Hospital of Pittsburgh of Upmc
Pittsburgh, Pennsylvania, United States
St. Jude Children'S Research Hospital
Memphis, Tennessee, United States
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States
Texas Children'S Hospital, Baylor College of Medicine
Houston, Texas, United States
Methodist Children'S Hospital of South Texas/texas Transplant Institute
San Antonio, Texas, United States

4 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Jun 2014
Primary completion: 30 Nov 2021
Completion: 30 Nov 2021
Last update posted: 2 Sept 2021
Registered enrollment: 1,480
Registry id: NCT02082353

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.