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Clinical trialNCT02135601CompletedInterventional

The Effects of the Water-exchanged Colonoscopy on Adenoma Detection Rate

SponsorAir Force Military Medical University, ChinaEnrollment3,303AdenomaPain
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Water exchange method has been shown to reduce medication requirement and pain experienced during colonoscopy. It may increase the adenoma detection rate (ADR). Water exchange provides salvage cleansing and the refractive index of water (n equals about 1.3) is larger than that of air, which creates optical distortion that likely contributes to objects appearing larger underwater, making smaller lesions easier to visualize and it may help draw attention to those smaller lesions during withdraw. These principles facilitate to the higher adenoma detection rate. There is a large number of literature on the adenoma detection rate during water exchange colonoscopy, but most studies have been conducted in only one centre, simple-size, and under sedation patients, the influence of adenoma detection rate under unsedation patients was unclear. The aim of this study is to compare the ADR of colonoscopy by using the water exchange method versus the conventional air method in unsedation patients in multiple centers in China.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

China
  • Chaoyang Hospital

    Beijing, Beijing Municipality, China

  • General Hospital of Guangzhou Military Command

    Guangzhou, Guangdong, China

  • Union Hospital of Tongji Medical College

    Wuhan, Hubei, China

  • Xijing Hospital of Digestive Diseases

    Xi'an, Shaanxi, China

  • Renji Hospital

    Shanghai, Shanghai Municipality, China

  • First Teaching Hospital of Xinjiang Medical University

    Ürümqi, Xinjiang, China

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Apr 2014
Primary completion
31 Jul 2015
Completion
31 Jul 2015
Last update posted
10 Nov 2015
Registered enrollment
3,303
Registry id
NCT02135601
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.