FindMyKOL
Clinical trialNCT02140255RecruitingPhase 1/PHASE2Interventional

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment1,120HIV Infection
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The study will explore the effects of early intensive antiretroviral therapy (ART) with or without a broadly neutralizing antibody (bNAb) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among infants living with HIV.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

  • Ellen Chadwick, MD

    Northwestern University Feinberg School of Medicine and Ann & Robert Lurie Children's Hospital of Chicago

    Study Chair
  • Jennifer Jao, MD

    Northwestern University Feinberg School of Medicine and Ann & Robert Lurie Children's Hospital of Chicago

    Study Chair

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

47 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Argentina
  • Hosp. General de Agudos Buenos Aires Argentina Nichd Crs

    Buenos Aires, Argentina

    Withdrawn
Brazil
  • Hospital Nossa Senhora Da Conceicao Nichd Crs

    Porto Alegre, Rio Greande Do Sul, Brazil

    Completed
  • 5073, School of Medicine Federal University Minas Gerais Clinical Research Site

    Minas Gerais, Brazil

    Recruiting
  • 5071, Instituto de Puericultura E Pediatria Martagao Gesteira Clinical Research Site

    Rio de Janeiro, Brazil

    Recruiting
  • 5072, Hospital Federal Dos Servidores Do Estado Clinical Research Site

    Rio de Janeiro, Brazil

    Completed
  • 5097, Hospital Geral de Nova Igaucu Clinical Research Site

    Rio de Janeiro, Brazil

    Completed
  • 5074, University of Sao Paulo Clinical Research Site

    São Paulo, Brazil

    Completed
Haiti
  • 30022, Les Centres Gheskio Clinical Research Site

    Port-au-Prince, Haiti

    Recruiting
Kenya
  • 5121, Kenya Medical Research Institute/walter Reed Project Clinical Research Center Kericho Clinical Research Site

    Kericho, Kenya

    Recruiting
Malawi
  • 12001, Malawi Clinical Research Site

    Lilongwe, Central Region, Malawi

    Recruiting
  • 30301, Blantyre Clinical Research Site

    Blantyre, Malawi

    Recruiting
Puerto Rico
  • 32513, Impaact/ Gamma Project/ Upr Pediatric Hiv/aids Research Network Crs

    San Juan, PR, Puerto Rico

    Withdrawn
  • San Juan City Hosp. Pr Nichd Crs

    San Juan, Puerto Rico, Puerto Rico

    Withdrawn
South Africa
  • Soweto Impaact Crs

    Johannesburg, Gauteng, South Africa

    Completed
  • Wits Rhi Shandukani Research Centre Crs

    Johannesburg, Gauteng, South Africa

    Completed
  • 30300, Umlazi Clinical Research Site

    Durban, KwaZulu-Natal, South Africa

    Recruiting
  • 8950, Famcru Clinical Research Site

    Tygerberg, Western Cape, South Africa

    Completed
Tanzania
  • 5118, Kilimanjaro Christian Medical Centre Clinical Research Site

    Moshi, Tanzania

    Recruiting
Thailand
  • 5115, Siriraj Hospital Mahidol University Clinical Research Site

    Bangkok, Bangkoknoi, Thailand

    Recruiting
  • 5116, Chiangrai Prachanukroh Hospital Clinical Research Site

    Chiang Mai, Thailand

    Recruiting
Uganda
  • 31798, Baylor-Uganda Clinical Research Site

    Kampala, Uganda

    Recruiting
  • Mu-Jhu Care Limited Crs

    Kampala, Uganda

    Completed
United States
  • 4601, University of California, San Diego Clinical Research Site

    La Jolla, California, United States

    Completed
  • 5048, University of Southern California Clinical Research Site

    Los Angeles, California, United States

    Recruiting
  • 5112, David Geffen School of Medicine at Ucla Clinical Research Site

    Los Angeles, California, United States

    Recruiting
  • 5052, University of Colorado, Denver Clinical Research Site

    Aurora, Colorado, United States

    Recruiting
  • 5055, South Florida Cdtc Fort Lauderdale Clinical Research Site

    Fort Lauderdale, Florida, United States

    Completed
  • 5051, University of Florida Center for Hiv/aids Research, Education and Service (uf Cares) Clinical Research Site

    Jacksonville, Florida, United States

    Recruiting
  • 5127, Pediatric Perinatal Hiv Clinical Research Site

    Miami, Florida, United States

    Withdrawn
  • Emory University School of Medicine Nichd Crs

    Atlanta, Georgia, United States

    Withdrawn
  • 32515, Rush Univ./cook County Hosp. Chicago Crs

    Chicago, Illinois, United States

    Recruiting
  • 4001, Lurie Children'S Hospital of Chicago Clinical Research Site

    Chicago, Illinois, United States

    Recruiting
  • 5083, Rush University Cook County Hospital Clinical Research Site

    Chicago, Illinois, United States

    Withdrawn
  • 5092, Johns Hopkins Clinical Research Site

    Baltimore, Maryland, United States

    Recruiting
  • Boston Medical Center Ped. Hiv Program Nichd Crs

    Boston, Massachusetts, United States

    Withdrawn
  • 5040, Suny Stony Brook Clinical Research Site

    Stony Brook, New York, United States

    Withdrawn
  • 5013, Jacobi Medical Center Clinical Research Site

    The Bronx, New York, United States

    Recruiting
  • 5114, Bronx Lebanon Hospital Center Clinical Research Site

    The Bronx, New York, United States

    Recruiting
  • Philadelphia Impaact Unit Crs

    Philadelphia, Pennsylvania, United States

    Withdrawn
  • 6501, St Jude Children'S Research Hospital Clinical Research Site

    Memphis, Tennessee, United States

    Recruiting
7 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Dolutegravir →Lopinavir →Nevirapine →Nucleoside Reverse Transcriptase InhibitorsRaltegravir →VRC01VRC07-523LS
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
23 Jan 2015
Primary completion
31 Jan 2028
Completion
31 Dec 2031
Last update posted
9 Sept 2026
Registered enrollment
1,120
Registry id
NCT02140255

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.