Clinical trialNCT02145377CompletedPhase 2Interventional

PXVX0200 (CVD103-HgR) vs Shanchol in Mali

SponsorUniversity of Maryland, BaltimoreEnrollment150Cholera

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To compare the ability of a single dose of PXVX0200 at two different dose levels, to placebo to elicit a significant antibody response 14 days after vaccination, compared to baseline. To compare the ability of a single dose of PXVX0200 to a comparator vaccine Shanchol, a two dose administration, to elicit antibody response by 14 days after vaccination.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Milagritos D Tapia, MD
University of Maryland, College Park
Principal Investigator
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Samba O Sow, MD, MS
Centre pour le Developpement des Vaccins - Mali
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Mali

Centre Pour Le Développement Des Vaccins, Mali (cvd-Mali)
Bamako, Mali

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PXVX0200 10E8PXVX0200 10E9PlaceboShanchol

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2014
Primary completion: 31 Mar 2015
Completion: 31 Mar 2015
Last update posted: 26 Sept 2019
Registered enrollment: 150
Registry id: NCT02145377

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.