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Clinical trialNCT02184117CompletedObservational

CONTRAST (Can cONTrast Injection Better Approximate FFR compAred to Pure reSTing Physiology?)

SponsorThe University of Texas Health Science Center, HoustonEnrollment763Coronary Artery Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine the diagnostic performances of iodine contrast medium and resting conditions to predict fractional flow reserve (FFR). Reference FFR will be measured using standard adenosine. We hypothesize that contrast FFR will offer superior diagnostic agreement compared to resting conditions.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium
  • Cardiovascular Center (olv-Ziekenhuis)

    Aalst, Belgium

France
  • Hôpital Louis Pradel

    Lyon, France

Italy
  • University of Naples Federico Ii

    Naples, Italy

Netherlands
  • Catharina Hospital

    Eindhoven, North Brabant, Netherlands

Portugal
  • Hospital Fernando Fonseca

    Lisbon, Portugal

South Korea
  • Asan Medical Center

    Seoul, South Korea

  • Seoul National University College of Medicine

    Seoul, South Korea

Sweden
  • Södersjukhuset

    Stockholm, Sweden

United Kingdom
  • Golden Jubilee National Hospital

    Clydebank, United Kingdom

United States
  • Stanford University, Palo Alto Va

    Palo Alto, California, United States

  • Integris Health

    Oklahoma City, Oklahoma, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Adenosine →Contrast MediaResting conditions
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jul 2014
Primary completion
31 May 2015
Completion
31 May 2015
Last update posted
16 May 2016
Registered enrollment
763
Registry id
NCT02184117
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.