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Clinical trialNCT02188160CompletedPhase 2Interventional

Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease

SponsorKala Pharmaceuticals, Inc.Enrollment150Dry Eye SyndromesKeratoconjunctivitis Sicca
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The primary purpose of this study is to determine the efficacy and safety of KPI-121 0.25% ophthalmic suspension compared to vehicle (placebo) in subjects who have a documented clinical diagnosis of dry eye disease. The product will be studied over 28 days, with 1-2 drops instilled in each eye four times daily (QID).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Sall Research Medical Center

    Artesia, California, United States

  • North Valley Eye Medical Group

    Mission Hills, California, United States

  • Martel Eye Medical Group

    Rancho Cordova, California, United States

  • Eye Center of Southern Ct, P.C.

    Hamden, Connecticut, United States

  • Price Vision Group

    Indianapolis, Indiana, United States

  • Ophthalmology Associates

    St Louis, Missouri, United States

  • Comprehensive Eye Care, Ltd. / Vision Research Institute, Llc

    Washington, Missouri, United States

  • South Shore Eye Center, Llp

    Wantagh, New York, United States

  • Abrams Eye Center

    Cleveland, Ohio, United States

  • Total Eye Care, Pa

    Memphis, Tennessee, United States

  • Whitsett Vision Group

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

KPI-121Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jun 2014
Primary completion
31 Jan 2015
Completion
31 Mar 2015
Last update posted
6 Jan 2021
Registered enrollment
150
Registry id
NCT02188160

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.