Clinical trialNCT02269592RecruitingObservational

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

SponsorDana-Farber Cancer InstituteEnrollment10,000B-cell Malignancy, Low-gradeHematological MalignanciesIgG Monoclonal Gammopathy of Uncertain SignificanceMonoclonal Gammopathy of Undetermined Significance (MGUS)Myelodysplastic Syndrome With Low-grade LesionsMyelodysplastic Syndromes+2 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Irene Ghobrial, MD
Dana-Farber Cancer Institute
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Irene Ghobrial, MD →
Recruiting
Dana Farber Cancer Institute at St. Elizabeth'S
Brighton, Massachusetts, United States
Olga Kozyreva, MD
Recruiting
Dana Farber Cancer Institute at Merrimack Valley
Methuen, Massachusetts, United States
Pedro Sanz-Altamira, MD
Recruiting
Dana Farber Cancer Institute at Milford Regional Medical Center
Milford, Massachusetts, United States
Michael Constantine, MD
Recruiting
Dana Farber Cancer Institute at South Shore
Weymouth, Massachusetts, United States
Irene Ghobrial, MD →
Recruiting
West Michigan Cancer Center
Kalamazoo, Michigan, United States
Mohammad Omaira, MD
Recruiting
Dana Farber/new Hampshire Oncology-Hematology
Londonderry, New Hampshire, United States
Jeanna Walsh, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2014
Primary completion: 31 Dec 2027
Completion: 30 Sept 2030
Last update posted: 7 May 2026
Registered enrollment: 10,000
Registry id: NCT02269592

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.