Clinical trialNCT02278874CompletedObservational

High Risk Multiple Gestation Study

SponsorNatera, Inc.Enrollment99Sex Chromosome AbnormalitiesTrisomy 13Trisomy 18Trisomy 21

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The objectives of the clinical study are to demonstrate the accuracy of our proprietary algorithm method to determine the genetic health of the developing fetuses in a multiple gestation pregnancy from a maternal blood sample. The long term goal of this study will be the development of a method of minimally invasive prenatal diagnosis that has a higher sensitivity and lower false positive rate in the intended population (e.g. multiple gestation pregnancies) than other currently available screening tests. This will result in fewer unnecessary amniocenteses and Chorionic Villus Sample (CVS) procedures, which are associated with a risk of miscarriage.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Errol Norwitz, MD, PhD
Tufts Medical Center
Principal Investigator
clinicaltrials.gov ↗
Joanne Stone, MD
Mt. Sinai Hospital, New York
Principal Investigator
clinicaltrials.gov ↗
Peer Dar, MD
Montefiore Medical Center
Principal Investigator
clinicaltrials.gov ↗
Rajeevi Madankumar, MD
Long Island Jewish Medical Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Tufts Medical Center
Boston, Massachusetts, United States
Long Island Jewish Medical Center
Glen Cove, New York, United States
Mt. Sinai Hospital
New York, New York, United States
Montefiore Medical Center
The Bronx, New York, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2014
Primary completion: 1 Dec 2018
Completion: 31 Mar 2019
Last update posted: 13 Jun 2019
Registered enrollment: 99
Registry id: NCT02278874

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.