Clinical trialNCT02298387CompletedPhase 1Interventional

A Phase 1 Study of OMP-305B83 in Subjects With Solid Tumors

SponsorOncoMed Pharmaceuticals, Inc.Enrollment71Advanced Solid Tumor Malignancies

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is an open-label Phase 1 dose escalation and expansion study of OMP-305B83 in subjects with previously treated solid tumors. Study includes a dose escalation phase and expansion phase. Subjects will be assessed for safety, immunogenicity, pharmacokinetics, biomarkers, and efficacy.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

David Smith, MD,FACP
University of Michigan
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Oncology Research Associates, Pllc D/b/a Pinnacle Oncology Hematology
Scottsdale, Arizona, United States
University of Colorado Anschutz Medical Campus
Aurora, Colorado, United States
University of Michigan Health System
Ann Arbor, Michigan, United States
University of Oklahoma Stephenson Cancer Center
Oklahoma City, Oklahoma, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

OMP-305B83

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 22 Dec 2014
Primary completion: 23 May 2017
Completion: 8 Sept 2017
Last update posted: 11 Aug 2020
Registered enrollment: 71
Registry id: NCT02298387

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.