Clinical trialNCT02407028RecruitingPhase 2Interventional

Hyperbaric Oxygen Brain Injury Treatment Trial

SponsorGaylan RockswoldEnrollment200Traumatic Brain Injury

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this innovative adaptive phase II trial design is to determine the optimal combination of hyperbaric oxygen treatment parameters that is most likely to demonstrate improvement in the outcome of severe TBI patients in a subsequent phase III trial.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Byron Gajewski, Ph.D.
University of Kansas Medical Center
Principal Investigator
clinicaltrials.gov ↗
Frederick K Korley, M.D., Ph.D.
University of Michigan
Principal Investigator
clinicaltrials.gov ↗
Gaylan L Rockswold, M.D., Ph.D.
Hennepin County Medical Center, Minneapolis
Principal Investigator
clinicaltrials.gov ↗
William Barsan, MD
University of Michigan
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Hamilton Heath Services
Hamilton, Ontario, Canada
Completed

United States

Ucsd Medical Center - Hillcrest Hospital
San Diego, California, United States
Jessica Weaver, MD
Recruiting
St. Mary'S Medical Center
West Palm Beach, Florida, United States
Faris Azar, MD
Recruiting
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Nicholas Mohr, MD
Recruiting
University of Kentucky Hospital
Lexington, Kentucky, United States
David Dornbos, MD
Recruiting
University of Maryland
Baltimore, Maryland, United States
Kinjal Sethuraman, MD
Recruiting
Detroit Receiving Hospital
Detroit, Michigan, United States
Anthony Lagina, MD
Recruiting
Hennepin County Hospital
Minneapolis, Minnesota, United States
Sam Cramer, MD, PhD
Recruiting
University of Nebraska Medical Center
Omaha, Nebraska, United States
Completed
Duke University Hospital
Durham, North Carolina, United States
Katherine Colton, MD
Recruiting
the Ohio State University Wexner Medical Center
Columbus, Ohio, United States
Completed

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Hyperbaric oxygenNormobaric Hyperoxia

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 25 Jun 2018
Primary completion: 26 Oct 2028
Completion: 30 Jun 2029
Last update posted: 2 Jun 2026
Registered enrollment: 200
Registry id: NCT02407028

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.