FindMyKOL
Clinical trialNCT02425904Active, not recruitingPhase 2Interventional

Study of Clofarabine in Patients With Recurrent or Refractory Langerhans Cell Histiocytosis and LCH-related Disorders

SponsorDana-Farber Cancer InstituteEnrollment25Langerhans Cell Histiocytosis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This research study is evaluating a drug called clofarabine as a possible treatment for Langerhans Cell Histiocytosis (LCH) and and other histiocytic disorders.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • the Hospital for Sick Children

    Toronto, Ontario, Canada

United States
  • Phoenix Children'S Hospital

    Phoenix, Arizona, United States

  • Arkansas Children'S Hospital

    Little Rock, Arkansas, United States

  • Children'S Hospital of Los Angeles

    Los Angeles, California, United States

  • University of California San Francisco Medical Center

    San Francisco, California, United States

  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

  • Boston Children'S Hospital

    Boston, Massachusetts, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, United States

  • Mount Sinai Medical Center

    New York, New York, United States

  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

  • the Children'S Hospital of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • St. Jude Children'S Research Hospital

    Memphis, Tennessee, United States

  • Texas Children'S Hospital

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 May 2015
Primary completion
31 Jan 2020
Completion
31 Dec 2026
Last update posted
23 Jun 2026
Registered enrollment
25
Registry id
NCT02425904

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.