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Clinical trialNCT02437136CompletedPhase 1/PHASE2Interventional

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)

SponsorSyndax PharmaceuticalsEnrollment191MelanomaMismatch Repair-Proficient Colorectal CancerNon-Small Cell Lung Cancer
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Yale University

    New Haven, Connecticut, United States

  • Emory University

    Atlanta, Georgia, United States

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, United States

  • University of Maryland, Marlene and Stewart Greenbaum Cancer Center

    Baltimore, Maryland, United States

  • Dana Farber Cancer Institution

    Boston, Massachusetts, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

  • the University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, United States

  • St Luke'S University Health Network

    Easton, Pennsylvania, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
26 Aug 2015
Primary completion
29 Sept 2022
Completion
29 Sept 2022
Last update posted
20 Mar 2025
Registered enrollment
191
Registry id
NCT02437136

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.