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Clinical trialNCT02442687CompletedPhase 2Interventional

JKB-121 for the Treatment of Nonalcoholic Steatohepatitis

SponsorManal AbdelmalekEnrollment65Nonalcoholic Steatohepatitis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the safety and potential efficacy of two dose levels of JKB-121 (5 mg twice daily and 10 mg twice daily) in reducing liver fat and/or liver biochemistry compared to placebo in patients with biopsy-proven nonalcoholic steatohepatitis

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Digestive Disease Specialists of the Southeast

    Dothan, Alabama, United States

  • Northwestern University Feinberg School of Medicine

    Chicago, Illinois, United States

  • Digestive Associates

    Las Vegas, Nevada, United States

  • Duke University

    Durham, North Carolina, United States

  • Digestive Disease Specialists

    Cincinnati, Ohio, United States

  • Brook Army Medical Center

    Houston, Texas, United States

  • University of Virginia Health Systems

    Charlottesville, Virginia, United States

  • Medical College of Virginia

    Richmond, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

JKB-121: 10 mg twice dailyJKB-121: 5 mg twice dailyPlacebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Aug 2015
Primary completion
24 Sept 2017
Completion
24 Sept 2017
Last update posted
7 Jan 2019
Registered enrollment
65
Registry id
NCT02442687

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.