Clinical trialNCT02453282Active, not recruitingPhase 3Interventional

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC)

SponsorAstraZenecaEnrollment1,118Non-Small-Cell Lung Carcinoma NSCLC

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Naiyer Rizvi, MD
Columbia University Medical Center, New York, NY, USA
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Stuart McIntosh, MD
AstraZeneca, Alderley Park, Cheshire, UK
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

196 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Research Site
Box Hill, Australia
Research Site
Gosford, Australia
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Kogarah, Australia
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Melbourne, Australia
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Port Macquarie, Australia
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Southport, Australia
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St Leonards, Australia

Belgium

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Brussels, Belgium
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Charleroi, Belgium
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Duffel, Belgium
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Leuven, Belgium
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Liège, Belgium

Canada

Research Site
Greater Sudbury, Ontario, Canada
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Kingston, Ontario, Canada
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Newmarket, Ontario, Canada
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Oshawa, Ontario, Canada
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Saint Catherines, Ontario, Canada
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Sault Ste. Marie, Ontario, Canada
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Toronto, Ontario, Canada
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Regina, Saskatchewan, Canada
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Saskatoon, Saskatchewan, Canada

France

Research Site
Bordeaux, France
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Brest, France
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Créteil, France
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Lille, France
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Lyon, France
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Marseille, France

Germany

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Aachen, Germany
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Bad Berka, Germany
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Berlin, Germany
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Berlin, Germany
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Freiburg im Breisgau, Germany
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Gauting, Germany
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Hamburg, Germany
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Heidelberg, Germany
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Hemer, Germany
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Homburg/Saar, Germany
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Immenhausen, Germany
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Löwenstein, Germany
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Lübeck, Germany

156 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 21 Jul 2015
Primary completion: 4 Oct 2018
Completion: 31 Dec 2026
Last update posted: 12 May 2026
Registered enrollment: 1,118
Registry id: NCT02453282

Cross-registrations

EU-CTR / CTIS (EudraCT)2015-001279-39

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.