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Clinical trialNCT02484378CompletedPhase 2Interventional

CER-001 Atherosclerosis Regression ACS Trial

SponsorCerenis Therapeutics, SAEnrollment301Acute Coronary Syndromes
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to assess the impact of ten intravenous infusions of 3 mg/kg CER 001 vs. placebo, given at weekly intervals for ten weeks, on atherosclerotic plaque volume as measured by coronary IVUS, when administered to subjects presenting with Acute Coronary Syndrome (ACS) with significant plaque volume.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

35 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Concord Repatriation General Hospital

    Concord, New South Wales, Australia

  • Liverpool Hospital

    Liverpool, New South Wales, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, Australia

  • Flinders Medical Centre

    Bedford Park, South Australia, Australia

  • Queen Elizabeth Hospital

    Woodville South, South Australia, Australia

  • Peninsula Heart Centre

    Frankston, Victoria, Australia

  • Epworth Research Institute

    Richmond, Victoria, Australia

  • Royal Perth Hospital

    Perth, Western Australia, Australia

Hungary
  • Military Hospital

    Budapest, Hungary

  • Semmelweiss University

    Budapest, Hungary

  • University of Debrecen

    Debrecen, Hungary

  • Pándy Kálmán County Hospital

    Gyula, Hungary

  • County Hospital of Kecskemet

    Kecskemét, Hungary

  • University of Szeged

    Szeged, Hungary

Netherlands
  • Meander Medisch Centrum

    Amersfoort, Netherlands

  • Onze Lieve Vrouwe Gasthuis

    Amsterdam, Netherlands

  • Scheper Ziekenhuis

    Emmen, Netherlands

  • Medisch Centrum Haaglanden

    Leidschendam, Netherlands

  • Canisius-Wilhelmina Hospital

    Nijmegen, Netherlands

  • Maasstad Hospital

    Rotterdam, Netherlands

  • Twee Steden Hospital (tilburg)

    Tilburg, Netherlands

  • Viecuri Medisch Centrum

    Venlo, Netherlands

United States
  • Heart Center Research, Llc

    Huntsville, Alabama, United States

  • Va San Diego Healthcare System

    San Diego, California, United States

  • Los Angeles Biomedical Research Institute at Harbor-Ucla Medical Center

    Torrance, California, United States

  • Va Eastern Colorado Health Care System

    Denver, Colorado, United States

  • Jacksonville Center for Clinical Research

    Jacksonville, Florida, United States

  • Cardiovascular Associates Research Llc

    Covington, Louisiana, United States

  • Cardiac and Vascular Research Center of Northern Michigan

    Petoskey, Michigan, United States

  • University of Missouri Health System

    Columbia, Missouri, United States

  • Buffalo Heart Group Llp

    Buffalo, New York, United States

  • Veterans Affairs Wny Healthcare System

    Buffalo, New York, United States

  • Novant Health Heart and Vascular Institute

    Charlotte, North Carolina, United States

  • South Oklahoma Heart Research, Llc

    Oklahoma City, Oklahoma, United States

  • Dallas Va Medical Center

    Dallas, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CER-001Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2015
Primary completion
30 Nov 2016
Completion
31 Dec 2016
Last update posted
11 Feb 2019
Registered enrollment
301
Registry id
NCT02484378

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.