Clinical trialNCT02536833CompletedPhase 2Interventional

A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects

SponsorBiosplice Therapeutics, Inc.Enrollment455Osteoarthritis

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Yusuf Yazici, M.D.
Biosplice Therapeutics, Inc.
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

36 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

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Mobile, Alabama, United States
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Phoenix, Arizona, United States
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Tucson, Arizona, United States
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El Cajon, California, United States
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Rancho Mirage, California, United States
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Spring Valley, California, United States
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Denver, Colorado, United States
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Clearwater, Florida, United States
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Coral Gables, Florida, United States
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Jacksonville, Florida, United States
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Miami, Florida, United States
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West Palm Beach, Florida, United States
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Woodstock, Georgia, United States
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Newton, Kansas, United States
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Wichita, Kansas, United States
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Lexington, Kentucky, United States
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Frederick, Maryland, United States
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Boston, Massachusetts, United States
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Worcester, Massachusetts, United States
Research Site 1
St Louis, Missouri, United States
Research Site 2
St Louis, Missouri, United States
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Orchard Park, New York, United States
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Rochester, New York, United States
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Raleigh, North Carolina, United States
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Salisbury, North Carolina, United States
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Cincinnati, Ohio, United States
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Duncansville, Pennsylvania, United States
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Mt. Pleasant, South Carolina, United States
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Rapid City, South Dakota, United States
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Knoxville, Tennessee, United States
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Austin, Texas, United States
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Houston, Texas, United States
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West Layton, Utah, United States
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Charlottesville, Virginia, United States
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Richmond, Virginia, United States
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Franklin, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 9 Sept 2015
Primary completion: 20 Apr 2017
Completion: 20 Apr 2017
Last update posted: 17 Mar 2021
Registered enrollment: 455
Registry id: NCT02536833

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.