Clinical trialNCT02546609CompletedPhase 2Interventional

The Effect Of NS-0200 Versus Placebo On Hepatic Fat Content In Patients With Non Alcoholic Fatty Liver Disease

SponsorNuSirt BiopharmaEnrollment91NAFLD

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this study is to determine if NS-0200 can reduce the amount of liver fat in patients diagnosed with non-alcoholic fatty liver disease (NAFLD). This study will compare two doses of NS-0200 to placebo in NAFLD patients.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Orville Kolterman, MD
NuSirt Biopharma
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Catalina Research Institute
Chino, California, United States
University of California San Diego
San Diego, California, United States
Rocky Mountain Research
Wheat Ridge, Colorado, United States
Atlanta Gastroenterology Associates
Atlanta, Georgia, United States
Gi Specialists of Georgia
Marietta, Georgia, United States
Northwestern University
Chicago, Illinois, United States
Indiana University
Indianapolis, Indiana, United States
University of North Carolina Chapel Hill
Chapel Hill, North Carolina, United States
Sterling Research
Cincinnati, Ohio, United States
Premier Clinical Research
Clarksville, Tennessee, United States
Gastro One
Germantown, Tennessee, United States
Quality Medical Research
Nashville, Tennessee, United States
Virginia Commonwealth University
Richmond, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Leu-Met-Sil 0.5Leu-Met-Sil 1.0Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 19 Nov 2015
Primary completion: 30 Nov 2016
Completion: 31 Jan 2017
Last update posted: 2 May 2018
Registered enrollment: 91
Registry id: NCT02546609

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.