Clinical trialNCT02588144UnknownInterventional

Combined Stimulation of STN and SNr for Resistant Freezing of Gait in Parkinson's Disease

SponsorUniversity Hospital TuebingenEnrollment54Parkinson's Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

54 patients with idiopathic Parkinson's disease and freezing of gait resistant to subthalamic nucleus stimulation and dopaminergic medication will be included into this multicentre randomised controlled double-blinded parallel group clinical trial. The treatment consists of two different stimulation settings using (i) conventional stimulation of the subthalamic nucleus \[standard STN\] as active comparator and (ii) combined stimulation of active electrode contacts located in both the subthalamic nucleus and substantia nigra pars reticulata \[STN+SNr\].

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Alireza Gharabaghi, MD
Division of Functional and Restorative Neurosurgery, Department of Neurosurgery, Tübingen, Germany, and Center for Integrative Neuroscience, Tübingen, Germany
Principal Investigator
clinicaltrials.gov ↗
Daniel Weiss, MD
Department for Neurodegenerative Diseases, Centre for Neurology, Tübingen, Germany, and Hertie-Institute for Clinical Brain Research
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Germany

Center of Neurology and Hertie Institute for Clinical Brain Research, Department for Neurodegenerative Diseases and Neurosurgery University of Tübingen
Tübingen, Baden-Wurttemberg, Germany
Recruiting
Ludwig-Maximilians-University Munich, Klinikum Großhadern, Department for Neurology and Neurosurgery
Munich, Bavaria, Germany
Recruiting
University Hospital Regensburg , Department for Neurology and Neurosurgery
Regensburg, Bavaria, Germany
Recruiting
University Hospital Köln, Department for Neurology and Neurosurgery
Cologne, North Rhine-Westphalia, Germany
Recruiting
University Hospital of Düsseldorf, Departments for Neurology and Neurosurgery
Düsseldorf, North Rhine-Westphalia, Germany
Recruiting
University Hospital Leipzig, Department for Neurology and Neurosurgery
Leipzig, Saxony, Germany
Recruiting
University Hospital Kiel, Department for Neurology and Neurosurgery
Kiel, Schleswig-Holstein, Germany
Recruiting
Charite- University Hospital Berlin, Departments for Neurology and Neurosurgery
Berlin, Germany
Recruiting
University Hospital Hamburg-Eppendorf, Department for Neurology and Neurosurgery
Hamburg, Germany
Recruiting

Luxembourg

University Hospital Luxembourg, Department for Neurology and Neurosurgery
Luxembourg, Luxembourg
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2015
Primary completion: 30 Sept 2017
Completion: 30 Sept 2017
Last update posted: 20 Jun 2017
Registered enrollment: 54
Registry id: NCT02588144

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.