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Clinical trialNCT02605434UnknownPhase 3Interventional

A Study to Assess the Safety and Efficacy of the of the Gastric-retentive AP-CD/LD in Advanced Parkinson's Patients

SponsorIntec Pharma Ltd.Enrollment420Parkinson's Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine whether the gastric retentive Accordion Pill™ Carbidopa/Levodopa (AP-CD/LD) is more effective than the commercially available immediate release Carbidopa/Levodopa in reducing motor fluctuations such as "off time" in advanced Parkinson's Disease patients.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

97 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Bulgaria
  • Mhat 'Sv.Pantaleymon - Pleven' Ood

    Pleven, Bulgaria

  • University Multiprofile Hospital for Active Treatment "sveti Georgi" Ead

    Plovdiv, Bulgaria

  • Clinic for Neurology and Sleep Medicine

    Sofia, Bulgaria

  • Clinic of Neurological Diseases

    Sofia, Bulgaria

  • Multiprofile Hospital for Active Treatment "sveta Marina'' Ead

    Varna, Bulgaria

Germany
  • Neuroakademie Alzenau Gbr

    Aschaffenburg, Germany

  • Praxis Für Neurologie Und Psychiatrie

    Berlin, Germany

  • Uniklinikum Carl-Gustav Carus An Der Tu Dresden

    Dresden, Germany

  • Technischen Universitaet Muenchen (tum) - Klinikum Rechts Der Isar

    München, Germany

  • Praxis Für Neurologie Und Psychiatrie

    Westerstede, Germany

Israel
  • Rambam Medical Center

    Haifa, Israel

  • Rabin Medical Center

    Petah Tikva, Israel

  • Chaim Sheba Medical Center at Tel Hashomer

    Ramat Gan, Israel

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, Israel

Italy
  • Ospedale Generale Regionale Francesco Miulli

    Acquaviva delle Fonti, Italy

  • Ospedali Riuniti Di Ancona

    Ancona, Italy

  • Spedali Civili Di Brescia Azienda Ospedaliera

    Brescia, Italy

  • Azienda Ospedaliera Universitaria Federico Ii

    Naples, Italy

  • Irccs Neurologico Fondazione "c. Mondino"

    Pavia, Italy

  • Azienda Ospedaliero-Universitaria Pisana

    Pisa, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli

    Roma, Italy

  • Irccs San Raffaele Pisana

    Roma, Italy

  • Azienda Ospedaliera Universitaria San Giovanni Di Dio Ruggi D'Aragona

    Salerno, Italy

  • Ospedale Di Circolo E Fondazione Macchi

    Varese, Italy

  • Azienda Unitá Locale Socio Sanitaria 12 Veneziana - Ospedale Dell'Angelo

    Venezia, Italy

  • Casa Di Cura Villa Margherita

    Vicenza, Italy

Poland
  • Centrum Medyczne Damiana Holding

    Warsaw, Masovian Voivodeship, Poland

  • Vitamed Galaj I Cichomski Spólka Jawna

    Bydgoszcz, Poland

  • Anna Kapustecka Prywatna Przychodnia Specjalistyczna Stomed

    Częstochowa, Poland

  • Centrum Medyczne Pratia Katowice I

    Katowice, Poland

  • Neuro-Care Site Management Organization Gabriela Klodowska-Duda

    Katowice, Poland

  • Krakowska Akademia Neurologii Sp. Z O. O.

    Krakow, Poland

  • Gabinet Lekarski Prof. Andrzej Bogucki

    Lodz, Poland

  • Centrum Medyczne Pratia Warszawa

    Warsaw, Poland

Slovakia
  • Neurologicka Ambulancia, Euro-Neuro S.R.O.

    Bratislava, Slovakia

  • Konzílium S.R.O.

    Považská Bystrica, Slovakia

  • Neuron - D.T. S.R.O.

    Žilina, Slovakia

Spain
  • Hm Puerta del Sur

    Móstoles, Madrid, Spain

  • Hospital Clinic I Provincial de Barcelona

    Barcelona, Spain

  • Hospital Universitari Quirón Dexeus

    Barcelona, Spain

57 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Accordion Pill™ Carbidopa/LevodopaPlacebo -AP-CD/LDPlacebo- SinemetSinemet®
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Mar 2016
Primary completion
31 Jul 2019
Completion
31 Dec 2019
Last update posted
8 Aug 2019
Registered enrollment
420
Registry id
NCT02605434

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.