Clinical trialNCT02667418TerminatedPhase 4Interventional

Optimal Treatment for Recurrent Clostridium Difficile

SponsorVA Office of Research and DevelopmentEnrollment308ClostridiumDifficileFidaxomicinVancomycin

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine whether fidaxomicin and vancomycin followed by taper and pulse vancomycin treatment are superior to standard vancomycin treatment for the treatment of recurrent Clostridium difficile infection.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Dale N Gerding, MD
Edward Hines Jr. VA Hospital, Hines, IL
Study Chair
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Stuart B. Johnson, MD BA
Edward Hines Jr. VA Hospital, Hines, IL
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

33 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

Va Caribbean Healthcare System, San Juan, Pr
San Juan, Puerto Rico

United States

Phoenix Va Health Care System, Phoenix, Az
Phoenix, Arizona, United States
Southern Arizona Va Health Care System, Tucson, Az
Tucson, Arizona, United States
Central Arkansas Veterans Healthcare System, Little Rock, Ar
Little Rock, Arkansas, United States
Va Loma Linda Healthcare System, Loma Linda, Ca
Loma Linda, California, United States
Va Long Beach Healthcare System, Long Beach, Ca
Long Beach, California, United States
Va Palo Alto Health Care System, Palo Alto, Ca
Palo Alto, California, United States
Va Northern California Health Care System, Mather, Ca
Sacramento, California, United States
Va San Diego Healthcare System, San Diego, Ca
San Diego, California, United States
Va Greater Los Angeles Healthcare System, West Los Angeles, Ca
West Los Angeles, California, United States
Rocky Mountain Regional Va Medical Center, Aurora, Co
Aurora, Colorado, United States
Bay Pines Va Healthcare System, Pay Pines, Fl
Bay Pines, Florida, United States
North Florida/south Georgia Veterans Health System, Gainesville, Fl
Gainesville, Florida, United States
James A. Haley Veterans' Hospital, Tampa, Fl
Tampa, Florida, United States
Atlanta Va Medical and Rehab Center, Decatur, Ga
Decatur, Georgia, United States
Jesse Brown Va Medical Center, Chicago, Il
Chicago, Illinois, United States
Edward Hines Jr. Va Hospital, Hines, Il
Hines, Illinois, United States
Edward Hines Jr. Va Hospital, Hines, Il
Hines, Illinois, United States
Rehabilitation R&d Service, Baltimore, Md
Baltimore, Maryland, United States
Va Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, Ma
Boston, Massachusetts, United States
Va Ann Arbor Healthcare System, Ann Arbor, Mi
Ann Arbor, Michigan, United States
John D. Dingell Va Medical Center, Detroit, Mi
Detroit, Michigan, United States
Asheville Va Medical Center, Asheville, Nc
Asheville, North Carolina, United States
Durham Va Medical Center, Durham, Nc
Durham, North Carolina, United States
Louis Stokes Va Medical Center, Cleveland, Oh
Cleveland, Ohio, United States
Oklahoma City Va Medical Center, Oklahoma City, Ok
Oklahoma City, Oklahoma, United States
Va Portland Health Care System, Portland, Or
Portland, Oregon, United States
Va North Texas Health Care System Dallas Va Medical Center, Dallas, Tx
Dallas, Texas, United States
Michael E. Debakey Va Medical Center, Houston, Tx
Houston, Texas, United States
South Texas Health Care System, San Antonio, Tx
San Antonio, Texas, United States
Va Salt Lake City Health Care System, Salt Lake City, Ut
Salt Lake City, Utah, United States
Va Puget Sound Health Care System Seattle Division, Seattle, Wa
Seattle, Washington, United States
Clement J. Zablocki Va Medical Center, Milwaukee, Wi
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Fidaxomicin →Vancomycin →Vancomycin with Taper/Pulse

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 19 Feb 2016
Primary completion: 7 Aug 2024
Completion: 31 Aug 2024
Last update posted: 21 Aug 2026
Registered enrollment: 308
Registry id: NCT02667418

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.