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Clinical trialNCT02727699CompletedPhase 2Interventional

A Phase II Study to Assess the Safety, Tolerability and Efficacy of Xanamem™ in Subjects With Mild Dementia Due to AD (XanADu)

SponsorActinogen MedicalEnrollment185Dementia, Alzheimer Type
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This XanADu Phase II study in mild Alzheimer's Disease (AD) is to assess the safety, tolerability and efficacy of Xanamem in subjects with mild dementia due to Alzheimer's Disease. Subjects will be randomized to receive either 10mg once daily Xanamem or Placebo at a 1:1 ratio in a double-blinded fashion.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

25 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Central Coast Neurosciences Research

    Central Coast, New South Wales, Australia

  • St Vincent'S Hospital Sydney

    Darlinghurst, New South Wales, Australia

  • Kara Institute of Neurological Diseases

    Macquarie Park, New South Wales, Australia

  • Medical & Cognitive Research Unit, Heidelberg Repatriation Hospital - Austin Health

    Heidelberg West, Victoria, Australia

  • Australian Alzheimer'S Research Foundation

    Nedlands, Western Australia, Australia

United Kingdom
  • the Research Institute for the Care of Older People

    Bath, Combe Park, United Kingdom

  • Manchester Mental Health & Social Care Trust - Dementia Research Office - Park House North Manchester General Hospital

    Manchester, Lancashire, United Kingdom

  • West London Mental Health Trust

    Isleworth, London, United Kingdom

  • St Pancras Clinical Research

    Kings Cross, London, United Kingdom

  • Institute of Clinical Sciences, Queen'S University Belfast

    Belfast, Northern Ireland, United Kingdom

  • Centre for Clinical Brain Sciences, Centre for Dementia Prevention, the University of Edinburgh

    Edinburgh, United Kingdom

United States
  • Tucson Neuroscience Research, Llc

    Tucson, Arizona, United States

  • National Research Institute

    Los Angeles, California, United States

  • Pcnd Neuroscience Research Institute

    Poway, California, United States

  • Pacific Research Network, Inc.

    San Diego, California, United States

  • Research Alliance Inc.

    Clearwater, Florida, United States

  • the Neurology Research Group, Llc

    Miami, Florida, United States

  • Compass Research Llc

    Orlando, Florida, United States

  • Imic, Inc.

    Palmetto Bay, Florida, United States

  • Atlanta Center for Medical Research

    Atlanta, Georgia, United States

  • Neurostudies.Net, Llc

    Decatur, Georgia, United States

  • the Neurocognitive Institute

    Mount Arlington, New Jersey, United States

  • Richmond Behavioral Associates

    Staten Island, New York, United States

  • Pmg Research of Rocky Mount, Llc

    Rocky Mount, North Carolina, United States

  • the Clinical Trial Center

    Jenkintown, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboXanamem™
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
23 Mar 2017
Primary completion
15 Mar 2019
Completion
15 Mar 2019
Last update posted
3 Feb 2025
Registered enrollment
185
Registry id
NCT02727699

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.