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Clinical trialNCT02734862CompletedPhase 2Interventional

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension

SponsorCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)Enrollment207CandidemiaFungal InfectionFungemiaInvasive CandidiasisMycoses
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine if intravenous CD101 is safe and effective in the treatment of candidemia and/or invasive candidiasis when compared to caspofungin (followed by oral fluconazole).

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

63 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium
  • Chu Brugman

    Brussels, Belgium

  • Erasme Hospital

    Brussels, Belgium

  • Jules Bordet Institute

    Brussels, Belgium

  • Ucl Saint-Luc

    Brussels, Belgium

  • Uz Gent Algemene Inwendige Zietken

    Ghent, Belgium

  • University Hospital Brussels

    Jette, Belgium

  • University Hospital Leuven

    Leuven, Belgium

  • Chu Sart-Tillman

    Liège, Belgium

Bulgaria
  • University Multiprofile Hospital for Active Treatment "sveti Ivan Rilski", Sofia, Clinic of Clinical Hematology

    Sofia, Bulgaria

  • University Multiprofile Hospital for Active Treatment and Emergency Medicine "n.I. Pirogov", Sofia, Burns and Plastic Surgery Clinic, Department of Anesthesiology and Intensive Care

    Sofia, Bulgaria

Canada
  • Juravinski Hospital and Cancer Centre/hamilton Health Sciences

    Hamilton, Ontario, Canada

  • Toronto General Hospital-University Health Network

    Toronto, Ontario, Canada

  • Ciusss de L'Est-de-L'Île-de-Montréal, Installation Hôpital

    Montreal, Quebec, Canada

  • Mcgill University Health Centre-Research Institute

    Montreal, Quebec, Canada

Greece
  • University General Hospital "attikon", 2nd Department of Critical Care

    Athens, Chaidari, Greece

  • General Hospital of Athens "evangelismos", 5th Department of Internal Medicine and Infectious Diseases Unit

    Athens, Greece

  • General Hospital of Athens "evangelismos", Department of Critical Care

    Athens, Greece

  • Henry Dunant Hospital Center

    Athens, Greece

  • Laiko General Hospital of Athens

    Athens, Greece

  • University Hospital of Larissa, Department of Critical Care Unit

    Thessaloniki, Greece

Hungary
  • Medical Centre, Hungarian Defence Forces, Central Intensive Care Unit and Anesthesiology Department

    Budapest, Hungary

  • Fejer County St. Gyorgy University Teaching Hospital, Central Department of Anesthesiology and Intensive Care Unit

    Szeged, Hungary

Italy
  • Polyclinic S. Orsola-Malpighi, Department of Organ Impairment and Transplants, Operative Unit of Infectious Diseases

    Bologna, Italy

  • University Polyclinic Hospital of Modena, Department of General and Specialist Surgery, Operative Unit of Anesthesia and Intensive Care I

    Modena, Italy

  • University Hospital of Pisa, Department of Gastroenterology and Infectious Diseases, Operative Unit of Infectious Diseases

    Pisa, Italy

  • University Polyclinic Agostino Gemelli, Complex Operative Unit of Infectious Diseases 2

    Rome, Italy

  • Hospital Maggiore University Hospital Ospedali Riuniti of Trieste Dept of Id

    Trieste, Italy

  • University Hospital "santa Maria Della Misericordia" of Udine, Department of Specialist Medicine, Clinic of Infectious Diseases

    Udine, Italy

Romania
  • Craiova County Emergency Clinical Hospital, Ati Clinic

    Craiova, Dolj, Romania

  • Institute of Infectious Diseases

    Bucharest, Sector 2, Romania

  • Pius Brinzeu County Emergency Clinical Hospital, Anesthesia and Intensive Care Department (romania)

    Timișoara, Timiș County, Romania

  • Sfanta Parascheva Parascheva Iasi Clinical Hospital for Infectious Diseases

    Iași, Romania

Russia
  • Kuban State Medical University

    Krasnodar, Russia

  • Territorial Clinical Hospital

    Krasnoyarsk, Russia

  • Mariinskaya City Hospital

    Saint Petersburg, Russia

Spain
  • Hospital Clinic I Provincial de Barcelona, Department of Infectious Diseases

    Barcelona, Catalonia, Spain

  • University Hospital Vall D'Hebron (huvh), Department of Infectious Diseases

    Barcelona, Catalonia, Spain

  • University Hospital Cruces, Unit of Infectious Diseases

    Barakaldo, Spain

  • Hospital del Mar, Department of Infectious Diseases

    Barcelona, Spain

  • General University Hospital Gregorio Maranon

    Madrid, Spain

23 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CD101CaspofunginFluconazoleIntravenous placeboPlacebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
26 Jul 2016
Primary completion
30 Jun 2019
Completion
31 Jul 2019
Last update posted
8 Dec 2020
Registered enrollment
207
Registry id
NCT02734862

Cross-registrations

EU-CTR / CTIS (EudraCT)2015-005599-51

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.