Clinical trialNCT02739542CompletedPhase 4Interventional

Assessment of Tecfidera® in Radiologically Isolated Syndrome (RIS)

SponsorUniversity of Texas Southwestern Medical CenterEnrollment87Multiple Sclerosis (MS)

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this investigation is to systematically study the efficacy of Tecfidera in those individuals who possess incidental white matter anomalies within the brain following a MRI study that is performed for a reason other than for the evaluation of MS (multiple sclerosis).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Darin T Okuda, MD
University of Texas Southwestern Medical Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Keck School of Medicine - Usc - Department of Neurology
Los Angeles, California, United States
Johns Hopkins University - Neurology
Baltimore, Maryland, United States
Mayo Clinic Department of Neurology
Rochester, Minnesota, United States
Washington University Department of Neurology
St Louis, Missouri, United States
Cleveland Clinic - Lou Ruvo Center for Brain Health
Las Vegas, Nevada, United States
Ms Clinical Care and Research Center, Dept of Neurology, Columbia University
New York, New York, United States
Oklahoma Medical Research Foundation, Ms Center of Excellence
Oklahoma City, Oklahoma, United States
Ms Treatment Center of Dallas
Dallas, Texas, United States
Ut Southwestern Medical Center
Dallas, Texas, United States
Swedish Medical Center
Seattle, Washington, United States
Multicare Institute for Research and Innovation
Tacoma, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboDimethyl fumarate →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 19 Mar 2016
Primary completion: 31 Mar 2021
Completion: 31 Mar 2021
Last update posted: 11 May 2022
Registered enrollment: 87
Registry id: NCT02739542

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.