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Clinical trialNCT02766465CompletedPhase 2Interventional

Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)

SponsorMedical College of WisconsinEnrollment138Sickle Cell Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a clinical trial that will compare survival and sickle related outcomes in adolescents and young adults with severe sickle cell disease after bone marrow transplantation and standard of care. The primary outcome is 2-year overall survival.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Mary Eapen, MD

    Center for International Blood and Marrow Transplant Research

    Study Director

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

35 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Benioff Children'S Hospital at Oakland

    Oakland, California, United States

  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

  • University of Florida Gainsville

    Gainesville, Florida, United States

  • Foundation for Sickle Cell Research/florida Sickle Inc.

    Hollywood, Florida, United States

  • University of Miami

    Miami, Florida, United States

  • Children'S Healthcare of Atlanta

    Atlanta, Georgia, United States

  • Emory University

    Atlanta, Georgia, United States

  • Grady Memorial Hospital

    Atlanta, Georgia, United States

  • Augusta University Medical Center

    Augusta, Georgia, United States

  • University of Iowa

    Iowa City, Iowa, United States

  • Children'S Hospital of New Orleans

    New Orleans, Louisiana, United States

  • Boston University

    Boston, Massachusetts, United States

  • Dana Farber Cancer Institute/brigham & Women'S Hospital

    Boston, Massachusetts, United States

  • Dana Farber Cancer Institute/massachusetts General Hospital

    Boston, Massachusetts, United States

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, United States

  • Washington University/st. Louis Children'S Hospital

    St Louis, Missouri, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, United States

  • Newark Beth Israel Medical Center

    Newark, New Jersey, United States

  • New York Presbyterian Brooklyn Methodist Hospital

    Brooklyn, New York, United States

  • Cohen Children'S Medical Center

    New Hyde Park, New York, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, United States

  • Weill Cornell Medical College

    New York, New York, United States

  • Montefiore Medical Center/albert Einstein School of Medicine

    The Bronx, New York, United States

  • University of North Carolina Hospital at Chapel Hill

    Chapel Hill, North Carolina, United States

  • Duke University Medical Center

    Durham, North Carolina, United States

  • Ohio State University

    Columbus, Ohio, United States

  • University of Oklahoma

    Oklahoma City, Oklahoma, United States

  • Oregon Health Sciences University

    Portland, Oregon, United States

  • Children'S Hospital of Philadelphia

    Philadelphia, Pennsylvania, United States

  • Medical University of South Carolina

    Charleston, South Carolina, United States

  • Baylor College of Medicine/the Methodist Hospital

    Houston, Texas, United States

  • University of Texas Health Sciences Center

    Houston, Texas, United States

  • University of Texas/md Anderson Crc

    Houston, Texas, United States

  • University of Virginia

    Charlottesville, Virginia, United States

  • Virginia Commonwealth University

    Richmond, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
16 Mar 2017
Primary completion
2 May 2023
Completion
2 Aug 2023
Last update posted
18 Apr 2025
Registered enrollment
138
Registry id
NCT02766465

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.